No. 1 (99) (2018) Problems of biology and medicine

Статьи

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  Metachronous breast cancer and possibilities of prognosis The RSO and RSMC Samarkand included 68 patients with metacarpenic breast cancer from 2007 to 2017. More than half of the patients were women of reproductive age (26-49 years). The difference between the primary and metacarpal cancer in unilateral cancer was detected at a very early stage of the disease. This is because patients with cancer treatment are in deep dosing. Metaxron is one of the major factors affecting the survival of patients with ovarian cancer: the second stage of cancer, the size of the tumor in the lactation, the volume of treatment, the rate of damage to the regional lymph nodes and the patient's age

  M Karimova , D Rakhmatov, Sh Shakhanova, D Akhmedzhanova

  50-51

  967   17

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  Formation and current status of agricultural items in the samarkand region After gaining independence by the republic, a cardinal rethinking of the existing structure and tasks of the health care system, formed in the Soviet era, its material and technical base was on the agenda.

  N Khodzhaev, Т Eshkobilov, B Abdullaev, Sh Rakhimova , A Bazarov

  192-195

  120   27

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  Analysis of neglected cases of cervical cancer in the samarkand region In this paper, the analysis of advanced cases of cervical cancer in recent years. The degree of dissemina-tion of tumor process at the time of diagnosis is the major prognostic factor that determines the course of the disease and fate of cancer patients. This trend is alarming, as the quality of services depends on the timely per-formance of diagnostic procedures and further treatment strategy and prognosis of malignant neoplasms

  Х Ortikova, M Oripova, Sh Khasanov , N Tolibova , N Urozov

  89-91

  96   17

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  Results of clinical-neurological and electroneyromyografy surgery of patients with vascular parkinsonism The peculiarity of the clinical course of Parkinsonism in patients with acute impairment of cerebral cir-culation was studied. We observed 58 patients with vascular Parkinsonism (VP) who underwent ischemic stroke, aged from 40 to 56 years. Patients were under our supervision for 20 days, who underwent clinical and neurological examination, ENMG, and also vegetative sphere research. Electroneyromyografy signs are early VP criteria, in the absence of clearly defined symptoms, and are manifested in the form of an increase in the rate of impulse conduction along efferent and afferent fibers

  Sh Ollanova, A Jurabekova

  85-88

  171   25

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  Rehabilitation of patients with type 1 diabetes with complicated gastroduodenitis We examined 70 patients with diabetes mellitus with complicated gastroduodenitis in the age of 7 to 17 years on the basis of the endocrinology department. The examination was carried out according to the stand-ard of examination of the endocrine patient with the inclusion of endoscopic examination. As a result of the survey it was established that the etiological factor ofgastroduodenitis in patients with type 1 diabetis is Helicobacter pylori infection.The incidence of infection correlates with the duration of diabe- tes mellitus,changes in the mucous membrane of the stomach and duodenum in children in the first year of the disease have a hyperactive plastic nature with a duration of diabetes up to 5 years of atrophic nature

  R Norshodieva, N Murtazaeva, N Karimova

  81-84

  155   23

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  The impact of iodinedeficiency states on the physical development of children We analyzed, the problem, of iodine deficiency by the example of the school region, distribution of frequency of endemic goiter depending on sex and age and revealed, negative influence of it on the parameters of children's physical growth and. development

  A Narbaev, G Kuvandikov, D Narzullaeva

  79-80

  117   21

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  Factorial analysis of tactic-diagnostic aspects, which impact on results of surgical treatment of mirizzi syndrome In this work conducted different factors, which one or the other stage impact on outcome of surgical treatment of Mirizzi syndrome. Accounting rare number of this complication, also it is occurred studying statis-tical indication of spreading MS in the structure of CBD and frequency of occurrence depending on variety type of operative intervention. Separately investigated versions of intraoperative technical complexity and ac-cordingly frequency of postoperative complications. It is divided into 4 groups among the different clinical-diagnostical and tactical-technical factors impact on outcome of surgical treatment: statistical, anamnestical, diagnostical, tactical and intraoperative

  F Nazyrov, M Akbarov, M Nishanov

  72-78

  79   24

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  Comparative analysis of characteristic indicators of patients with ovarian cancer The article discusses the comparative analysis of characteristic parameters of patients with ovarian can-cer. We made a questionnaire for them to study the lives of these patients. The questionnaire contains 17 ques-tions that determine the anamnesis of patients. And willing patients were allowed to respond anonymously

  Х Mukhtarzhanova, G Ermatova, D Kayumov, S Yakubbekova , D Mamarasulova, M Karimov

  70-71

  107   20

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  The hymenolepidosis in the structure of the intestinal helminthiasis in the Uzbekistan In Uzbekistan, in the structure of intestinal helminthiasis, hymenolepiasis is 16.9%. The material for the study was the reporting data of the Republican Center for State Sanitary and Epidemiological Surveillance for the survey of the population for helminthiases. The specific gravity of hymenolepiasis in the structure of hel-minthiases in Tashkent and in all regions of the republic was analyzed

  L Mahmudov

  67-69

  167   44

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  Frequensy of cognitive and non- cognitive disturbances in patients with young age with chronic cerebrovaslar diseases with conditioned arterial hypos and hypertension Cerebrovacular diseases can for a long time only be manifested by cognitive impairment. More than 1/3 of the examinations revealed discirculatory encephalopathy of the 1 st stage, mild and moderate cognitive im-pairment appeared in the first and second stages of discirculatory encephalopathy (DE). Symptoms of anxiety in patients with chronic cerebrovascular pathology in 92,8% of cases were observed in stage II stage discircu-latory encephalopathy due to arterial hypertension and in 89,6% with second stage discirculatory encephalo-pathy due to essential arterial hypertension(EAG)

  M Mamurova, A Jurabekova, Sh Ruzieva , Sh Tursunova

  63-66

  127   20

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  The value of helical computer tomography and magnetic resonance imaging in the diagnosis of juvenile angiofibroma of the nasopharynx Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor that occur most often in males with ger-mination her in the nose and paranasal sinuses (PPN). For getting reliable information in the diagnosis of tu-mor is of great importance of CT and MRI. This method allows to obtain information about the status of such inaccessible during operation areas, such as pterygopalatine and infratemporal fossa, sphenoid sinus, posteri-or orbit, tissue parapharyngeal space

  G Lutfullaev, P Takhirjanova, D Fayzullaeva

  60-62

  113   22

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  Профилактика венозных тромбоэмболических осложнений у беременных с варикозным расширением вен малого таза The use of 600 mg phlebodia in pregnant women with varicose veins of the pelvis is pathogenically grounded and effective. The reduction of the main clinical manifestations of this pathology in combination with the stabilization of the disturbed parameters of the blood coagulation system made it possible to prevent such formidable complications of pregnancy as venous thromboembolic complications in pregnant women at high risk

  M Kurbaniyazova

  57-59

  120   32

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  Modern epidemiological aspects of acute intestinal infections in the samarkand region The article discusses the results of the epidemiological analysis of the incidence of acute intestinal infec-tions registered in the Samarkand region in the period from 2012 to 2016. Based on the results of a survey of parents of children hospitalized in the Samarkand Oblast Infectious Disease Hospital for diarrhea, an analysis is made of the pathways and factors of infection, as well as the conditions that contributed to the development of the disease. The insufficient awareness of mothers about the rational feeding of children, the primary measures that parents should take when diarrhea syndrome occurs in young children (in particular, the signifi- cance and methodology of oral rehydration) has been identified

  M Krasnaya, G Mustaeva

  52-56

  171   39

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  Complex approach to the treatment of patients with dystrophic diseases Of vulva in different age groups The premalignant diseases of the skin and mucosa of external genitalia are dystrophic diseases of the vulva against which in 20-60% of cases there is cancer. The material of this study selected a retrospective analysis of 50 patients treated for dystrophic diseases of the vulva. As a result of the treatment of dystrophic diseases of the vulva in women of reproductive age, drug treatment with hormone therapy (local and general use) and cryodestruction, is a more effective and minimally invasive method. In menopausal age and climacter-ic age in women due to of the in effectiveness of drug treatment without hormone therapy in most cases leads to the application of surgical intervention

  Zh Abdurakhmanov, M Karimovа , F Orifova, M Oripova

  5-6

  65   22

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  Combined endoscopic gemostaz under ulcerous bleedings To influence the source of bleeding with an endoscope, various methods of endoscopic hemostasis are used. In the endoscopic service, such methods of hemostasis as: thermal (electrocoagulation), injectable (infiltrative) (adrenaline, ethanol, sclerosants), mechanical (endocliping) are used. As a result of the analysis of clinical studies conducted in 625 patients with gastroduodenal bleeding, among which in 283 cases continued bleeding. It has been proved that the active use of both traditional and high-tech methods of endoscopic hemostasis, which have high efficiency with continuing bleeding and which has taken place, contributes to a reduction in the number of forced operations.

  R Kadyrov, YU Ahmedov, F Mizamov, N Kurbonov, B Normamatov

  47-49

  134   39

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  Bioelektric activity of the brain in children with consequences of perinatal injuries of the central nervou system The bioelectrical activity and its changes on the EEG have been studied, which reflect the severity of functional disorders and are manifested by various pathological phenomena, the correct interpretation of which allows one to assess the degree of functional disorders of the central nervous system

  L Igamova, A Jurabekova, N Dzhumaev, F Usmanova

  43-46

  242   26

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  The role of the nurse for the prevention of uterine cervical diseases Correct and competent organization of the nurse's work of the examination room, contributes to the in- crease of detectability of cervical disease and can be one of the most promising and effective forms of preven-tive examination of the female population

  S Zhalilova

  40-42

  503   230

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  Change in cerebral hemodinamics in patients with discirculatory encephalopathy with intravenous ozone therapy The aim of the study was to evaluate the effect of intravenous ozone therapy (OT) on the indices of cere-bral hemodynamics in patients with different stages of dyscirculatory encephalopathy. Patients are divided into groups: one of the groups on the background of traditional treatment received a course of OT. ОТ leads to an increase in anticoagulant activity, the linear velocity of blood flow along the common carotid artery and along the internal carotid artery by means of ultrasound dopplerography was reliably normalized, the indices on the main arteries of the head on the extracranial level were normalized

  J Dzhurakulov, A Jurabekova , N Abdullayeva , Sh Tursunova

  36-39

  213   21

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  Changes of cardiovascular system in adolescents in obesity and arterial Hypertension 61 adolescents with obesity and hypertension were examined. It was revealed that the development of myocardial hypertrophy is affected by body mass, blood pressure level, vasoconstriction processes, as well as insulin resistance and atherogenic dyslipidemia. These parameters can serve as early markers of myocardial hypertrophy. Also, in children with obesity and hypertension, in 1/5 of cases a complete metabolic syndrome was found and in 1/3 of cases an incomplete metabolic syndrome, which requires immediate treatment of this condition, to prevent early complications and disability of adolescents in the adult period

  L Garifulina, M Ashurova , Z Holmuradova

  33-35

  124   24

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  Assessment of the perinatal risk of premature birth in women with Pulmonary tuberculosis The analysis of factors of perinatal risk of premature birth in women with pulmonary tuberculosis is conducted. A high perinatal risk of obstetrical complications on the background of the tuberculosis process is established. It is shown that under tuberculosis the premature birth is a cause of perinatal pathology, morbidi-ty, disability, and child mortality. It is proved that perinatal pathology and mortality are associated or deter- mined by premature birth and leads to an increase in the level of insufficient weight to the term of gestation of children, and the mortality in this category of newborns is 33 times higher in comparison with full-term chil-dren

  V Garbuzyuk, S Polevaya, V Polevoy

  30-32

  101   22

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  Immediate results of intra-regional auutoplasmic therapy in the Integrated treatment of local-distributed tongue cancer and bottom Side In the article direct results of regional intraarterial and intraoperative autoplasmochemotherapy as a component of complex antitumoral treatment of cancer of the bottom of the oral cavity and tongue were studied. The obtained data testify to a sufficiently high efficiency, safe toxic profile and positive dynamics of immunoregulatory proteins in regional intraarterial and intraoperative autoplasmochemotherapy as a component of complex antitumor treatment in patients with cancer of the bottom of the mouth and tongue

  A Ganiev, M Khalmatova

  27-29

  115   29

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  The results of surgical treatment of acute cholangitis and its Consequences From 2014 to 2017 at the surgical Department of the Samarkand city medical Association was on in- spection and treatment of 236 patients with acute cholangitis. In our work, patients given the causal factors of acute cholangitis were divided into 4 groups: 1-gallstone disease and its complications 75,8% (179); 2-tumors of the pancreatobiliary zone of 10.2% (24); 3-cicatricial strictures of the bile ducts of 5.1% (12); 4-parasitic liver lesions were 8.9% (21). As shown by the results of our study, the vast majority (92,8%) were patients of cholelithiasis and its complications. In this group operation was cholecystectomy with different types of drain- age ductal system. As acute cholangitis and its consequences are a distinctive couple, biliary obstruction withpolyetiological character, individual approach to the selection of a program optimized diagnosis and treatment is mandatory. Expediently the allocation of groups of patients according to etiological factors of acute cholan-gitis, severity of the disease and its consequences, defining rational diagnostic, tactical and technical decisions

  A Babazhanov , A Toirov, A Ahmedov, E Khudoiberdiev, B Mukhitdinov

  23-26

  109   19

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  The functional status of residual thyroid tissue after surgery of benign Thyroid diseases Within the population surveyed (64) patients were included, 48 women and 16 men, ranging in age from 17 to 72 years. The average age was 44.6±5.3 years, due to the feature of the disease thyroid, more than three times more common in women of working age. Analyses of results show that three or more prognostic factors in maintaining euthyroid in the postoperative period, possible implementation of a Subtotal resection is the preparation of a clinically significant volume of tissue thyroid

  A Babazhanov , A Ahmedov, F Muhammadkulov , G Normuradova

  20-22

  174   26

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  Effect of complex treatment on indicators of endogenous intoxication in Chronic pyelonephritis in children Theaim of this work was an attempt to evaluate the effect of сomplex treatment on some endogenous in-toxication indicators in chronic pyelonephritis developed on the background of dismetabolic nephropathy (DMN) (DCHP). Patents and methods. A survey of 130 children DCHP, aged 4 to 15 years. Patients were di-vided into 3 groups depending on treatment method. Results. Comparative assessment of the results of the study of endogenous intoxication conducted after treatment in children with DСHP, depending on the method of treatment, demonstrated the effectiveness of "renal tyubazh" compared to other methods of therapy. Conclu- sion. The use of complex treatment of "renal tyubazh" when DCHP is the most appropriate method of therapy. This method leads to the restoration of the TCA (total concentration of albumin) and ECA (effective concentra-tion of albumin) in the blood, TCA and SMP (medium molecular peptides) in the urine

  N Akhmedzhanova , M Egamberdieva, X Rahimov

  14-19

  127   33

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  Anthropometric indicators for chess children It has been established that the anthropometric indices of students of 7-11 years of both sexes engaged in chess correspond to age and gender standards. While students of 4 grades of both sexes who have been engaged in chess for more than 3 years have a higher academic performance in the subjects "mathematics" and "informatics", however, in this cohort of children the morbidity rates are higher, especially with signs of vegetative changes (45%)

  N Alieva , F Mukhamedzhanova

  11-13

  153   30

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