All articles - Obstetrics and Gynecology
Number of articles: 652
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EFFECTIVENESS OF OZONE THERAPY USING IN THE COMPREHENSIVE TREATMENT OF PREGNANCY NON-CAREThe results of clinical studies on the biological effects of ozone therapy are summarized. A critical analysis of the data obtained using ozone therapy in obstetrics was performed. It is argued that the action of reactive oxygen species is determined, firstly, by the concentration of ozone, and secondly, by the stage of the pathological process. The problems of ozone therapy are analyzed and suggestions are made on the prospects for the development of ozone technologies in medicine.
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The article presents the results of reproductive age 126 women survey with genital prolapse receiving treatment in the 3rd maternity complex of the Samarkand city for the period from 2012 to 2016. It has been established that the developed method of surgical correction of genital prolapse with simultaneous transvaginal ligation of the fallopian tubes in women of reproductive age will not only eliminate the main pathology, but also choose the most effective and safe contraception method for women with genital prolapse, reduce treatment time, improve the quality of life, reduce economic costs. -
Uterine myoma is relatively rare in women aged 20-30, but disease risk increases significantly after the age of 35-40. The need to preserve fertility occurs in women of late reproductive age with uterine myoma also increases. Conservative myomectomy is considered to be the method of choice for surgical treatment of uterine myomas in reproductive period. The article describes types and techniques of conservative myomectomy. -
RUPTURE OF AMNIOTIC MEMBRANES IN PRETERM, AS A FACTOR IN THE DEVELOPMENT OF OBSTETRICS COMPLICATIONS1 ms article presents tne results or tne retrospective study or tne cniiamrtn nistory or iuo pregnant women in whom labor was complicated by premature rupture of the membranes, delivery in the Bukhara regional perinatal center for the period 2017-2019 years. The results show the significant role of premature rupture of the membranes in the development of obstetrics and perinatal complications, especially in women with a history of somatic and gynecological anamnesis
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CONDITION HEMODYNAMIC AND MORPHOLOGICAL PARALLELS WOMEN WITH PREMATURE GENUS IN ANAMNESIS68 pregnant women were examined, whose pregnancy ended with premature birth in the gestation period of 22-36 weeks. Changes in the mother-placenta-fetus system, changes in the placental system in the system, connection of morphological changes between the placenta and the endometrium of the uterus, as well as their comparative analysis, were examined.
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The purpose of lhe study: to evaluate the state of hem coagulation with its physiological course for predicting the risk of obstetric hemorrhage in terms of trimesters of pregnancy in its dynamics. Surveyed 65 women with physiological pregnancy. Of these, 30 women (group II) have risk factors; smoking patients during this pregnancy, overweight. taking oral contraceptives with the abolition of less than or 3 months before pregnancy. 35- Women without risk factors with a normal pregnancy. Clinical and hcmostasiologic studies were performed for periods of 10-12, 22-24, and 35-36 weeks of gestation. During gestation, there was an increase in spontaneous platelets, an increase in fibrinogen level. D-dimer. and a slowdown in fibrinolysis. -
Acyclic uterine bleeding is a formidable complication of the menopause, and remains relevant to this day. The data of world literature shows that there is no consensus on the data on the pathological condition of the endometrium. In this connection, the attention of world researchers is drawn to a further study of the state of the endometrium, depending on the cyclic changes in the endometrium, in order to identify preventive measures for acyclic uterine bleeding. -
PROGNOSIS AND PREVENTION OF OBSTETRIC AND PERINATAL COMPLICATIONS IN MULTIPLE PREGNANCIESThe increased interest in multiple pregnancy (MNPB), characteristic since ancient times, has not weakened to the present [12,21,22]. The frequency of multiple pregnancies (MNPB) in most European countries ranges from 0.7-2.5% and tends to steadily increase [15,25,27,32].
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ALTERNATIVE VARIANTS OF THE PREVENTIVE MAINTENANCE AND TREATMENTS OF THE CLI- MACTERIC SYNDROME AND COMORBID CONDITIONS WITH ITIn order to increase the effectiveness of medical care for women with polymorphic pathology in perimenopause, it is necessary to re-evaluate and improve it, develop therapeutic and preventive strategies that would effectively correct several risk factors, thereby reducing polypragmasia [31]. Manifest problems of estrogen deficiency significantly worsen the health of women in perimenopause and throughout subsequent life, therefore, the search for optimal methods and approaches to prevention and treatment has not only medical, but also social significance.
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Preeclampsia is a multisystem disorder that complicates 3-5% of pregnancies and remains one of the main causes of maternal and neonatal morbidity and mortality. This pathology is characterized by hypertension and proteinuria after 20 weeks of pregnancy and often leads to endothelial dysfunction and obstetric complications in the future [1;2]. To date, there is no effective preventive therapy, and childbirth remains the only approach to the prevention of maternal morbidity and mortality. However, this is usually achieved due to premature birth and related complications and pathological processes that are involved in the subsequent [3]. -
Infectious and inflammatory diseases of the female reproductive system occupy an important place in the structure of infectious inflammatory diseases in general. According to the authors, inflammatory diseases of the female genitourinary system account for about 60-65% of all gynecological diagnoses in general. Almost every woman has applied at least once in her life for inflammatory diseases of the female reproductive system [II], and the time and other costs of their treatment cannot be underestimated. However, the therapy of this category of diseases is not always successful, it can not always be considered successful. Both relapses and complications are possible, often leading to multiple repeated referrals [9, 46]. One of the most widespread diseases of the female genital area can be considered vulvovaginitis - an inflammatory disease of the vulva and vagina, typical symptoms of which can be considered irritation of the vulva, which may include burning, itching with vaginal discharge. With atypical or -
LOW OVARIAN RESERVE AS AN URGENT TYPE OF FEMALE INFERTILITY FOR TREATMENT AND PREPARATION FOR IN VITRO FERTILIZATIONA decrease in ovarian reserve is a phenomenon that is often observed in women aged 30 to 39 years, but can also affect young women. It is believed that at the age of 37-38 years, there is an accelerated decrease in the follicular reserve to a critical level of 25,000. Subsequently, there is a very limited time for conception with your own eggs. It is believed that this phenomenon is accompanied by a deterioration in quality due to aging of oocytes and, consequently, young women with low ovarian reserve (NOR) may still have a better chance of conception. However, recent data dispute this, and the NOR associated with a low probability of pregnancy and a high probability of pregnancy loss is independent of age [1,2].
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Introduction. According to the literature, the prevalence of idiopathic thrombocytopenic purpura (ITP) among adults and children ranges from 1 to 13 per 100,000 people. It is known that among patients with ITP, women predominate in the ratio of 3.9:1, and at reproductive age this ratio increases to 9:1. in obstetric and hematology practice [6]. Fertility in patients with ITP usually does not suffer, however, severe exacerbations of the disease and the use of high doses of corticosteroids or cytostatic immunosuppressors (azathioprine, cyclophosphamide, etc.) in their treatment cause oligo- and amenorrhea. There are no data on the effect on fertility of other drugs commonly used in the treatment of ITP. According to K. Gill (2000), among women of childbearing age, ITP occurs with a frequency of 1:59 per 1000 live births, which is about 3% of all cases of maternal thrombocytopenia during childbirth [12]. According to A. Faridi, thrombocytopenia (<150,000/µl) is a common finding, the frequency of -
SUCCESSFUL SURGICAL CORRECTION OF THE GENITAL MALFORMATIONS AFTER UNNECESSARY SURGICAL OPERATIONSCongenital malformations of the female genital organs account for about 14% of all congenital malformations. The frequency of abnormal development of the vagina and uterus is 1 case per 300 newborn girls [3].
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SOME BIOCHEMICAL MECHANISMS OF ENDOTHELIAL DYSFUNCTION IN WOMEN WHO HAVE UNDERGONE MASSIVE BLEEDING DURING CHILDBIRTHWe have conducted studies 1 -4 days after bleeding. Depending on the severity of the condition of pregnant women during childbirth and medical measures taken, the patients were divided into 2 groups: the first group included 20 women who underwent organ-preserving operations, the second group included 16 women with removal of the uterus and her appendages. Our studies showed a statistically significant increase in the level of homocysteine in the blood serum of women of the 1st group by 2.05 (P <0.01) times relative to the values of practically healthy women in labor. However, the level of ET-1 and PV did not significantly differ from the values of healthy women in childbirth.
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Preterm birth is one of the most important aspects of the problem of protecting the health of the mother and child. Premature infants account for 60-70% of early neonatal mortality and 65-75% of infant mortality. Stillbirth in premature births is observed 8-13 times more often than with timely deliveries. Perinatal mortality in preterm infants is 33 times higher than in full-term. -
The article analyzes the features of surgical treatment of repeated prolapse of the uterus and vaginal walls after various operations. We studied 36 patients with prolapse of the internal genital organs after various operations from 45 to 62 years. All women undergo generally accepted mandatory general clinical and gynecological research methods. We studied the methods of surgical tactics of prolapse of genital organs after surgery. -
Determination of reserves to reduce the frequency of cesarean section in the perinatal center using the Robson classificationThis study was performed in Republican Perinatal Center in Uzbekistan, from January 1, 2017 to De-cember 31, 2017. All women delivered during this period were classified according to the Robson classification consisting of 10 groups using their maternal characteristics and obstetric history. There were 5551 births, of which 1966 - from cesarean section. Robson's classification made it possible to determine the dynamics and reserves to reduce the caesarean section in the perinatal center: to increase vaginal birth after cesarean, vaginal birth at breech presentations, use a partograph to make a decision for the diagnosis of obstructive labor, suggest external cephalic version at breech presentation, develop a guideline on obstetric tactics in pregnant women with cardiac arrhythmias.
Journal problems of biology and medicine -
The review presents current data on the problem of sleep disorders in pregnant women, as well as the impact ot sleep disorders on the course of pregnancy, the development of obstetric complications and birth outcomes. -
Studying of components of a metabolic syndrome at women in a menopause, will allow estimating preva-lence, a pathogeny of development of MS, at early stages of its forming and considering influence of the andro-genic status timely to appoint hormonal correction, for reduction of risk of metabolic "adverse" visceral obesity and to carry out prevention of cardiovascular complications -
The purpose of this work was to study the mathematical modeling of primary and secondary placental insufficiency and to study the morphological and morphometric parameters of the placenta of 20 women in labor and to conduct mathematical modeling. -
PATHOMORPHOLOGICAL AND MICROBIOLOGICAL PARALLELS OF THE PATHWAYS OF INFECTION OF THE PLACENTA IN WOMEN WITH REPRODUCTIVE FETAL LOSS DURING A PANDEMICIn connection with the development of medicine and the improvement of the perinatal service, the frequency of fetal loss has decreased 10 times. There was a significant decrease in the level of intrapartum and neonatal mortality, however, the level of reproductive fetal loss remains high. The article presents data on the morphological features of the placenta in 47 pregnant women with reproductive fetal loss at a gestational age of 21 to 41 weeks. In the placenta of women with reproductive fetal loss, colony forming steptococcus, dominated among aerobes, and Eubacleriuni sp. among anaerobes.
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FETAL DEVELOPMENT AND COMPLICATIONS DURING PREGNANCY IN WOMEN WITH CHRONIC KIDNEY DISEASEThe article describes the relationship between the concepts of chronic kidney disease. The data on the prevalence of chronic kidney disease among women of reproductive age and the effect on fetal development arc presented. The frequency and nature of obstetric and perinatal complications and pregnancy outcomes in this group of women are described. The features of pregravidar preparation, pregnancy management, delivery tactics and follow-up in the postpartum period of patients with chronic kidney disease arc considered.
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The new coronavirus disease COVID-19 has spread rapidly around the world. In December 2019, the new coronavirus was first reported in Wuhan. Hubei province. China. In the following months, widespread transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the 2019 coronavirus disease (COVID-19), has been reported across all inhabited continents. In Uzbekistan, the first recorded case on March 6, 2020. Currently, at the time of this writing. 65,765 COVID-19 cases with a positive test and 2,289 deaths have been reported in Uzbekistan. Although awareness of the disease continues, information on pregnancy remains limited. -
ASSESSMENT OF IMMUNE STATUS AND EFFICIENCY OF IMMUNE CORRECTION OF INFLAMMATORY DISEASES OF THE PELVIC ORGANS IN WOMENThe aim of the study was to review and analyze the literature on the definition and condition of the immune system and the effectiveness of immune corrective measures. It was found that in acute and chronic IDPO (inflammatory diseases of the pelvic organs) the development of secondary immunodeficiency was noted, expressed by a decrease in the indicators of cellular and humoral immunity, multidirectional changes in pro- and antiinflammatory cytokines in patients. Almost all authors were unanimous in the opinion that immune corrective therapy should be used for inflammatory diseases of the pelvic organs, while offering various immune correctors.
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