All articles - Rheumatology
Number of articles: 85
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TRIPLE OSTEOTOMY OF THE PELVIS IN TREATMENT OF HIP DYSPLASIA IN CHILDREN AND ADOLESCENTSThe article analyzes the results of treatment of 18 patients (22 joints) treated for residual hip dysplasia. The patients' age ranged from 7 to 14 years. Among the sick boys there were 6, girls 12. The examination of patients was carried out with using clinical, X-ray and computed tomography methods with the construction of a three-dimensional model of the hip joint. The results of surgical treatment were assessed as excellent, good, satisfactory and unsatisfactory. Excellent treatment results were obtained in 4 patients. Good results were observed in 10 patients. Satisfactory results were observed in 4 patients.
Doctor's Herald -
The article discusses the issues of surgical treatment of patients with patellar instability. The choice of many surgical methods for treating patellar instability is an urgent problem. Not all are pathogenetically good and do not address the root cause of the problem. Based on clinical practice and the experience of the authors, pathogenetic surgery is recognized as an advantage of the proposed method. -
Improvement of methods of pre-operational preparation of scoliotic disease in childrenIndications Application optymyzyrovannoho preoperative medical- diagnostically complex for the train-ing of paravertebral tissues and contents of the spinal canal k radykalnoy correction in children co skolyoty-cheskoy illness IV degree. Predlahaemыy method of rasshyryaet abilities Almost orthopedic vertebrologist As-sist in aid to children with data disease
Journal problems of biology and medicine -
The article points to the opinion on the relationship between the successful use of calcium alginate, as one of the calcium-containing compounds in changing the main biochemical parameters of blood, by compacting bone beams, as the main indicator of the intensity of strengthening the growth of bone tissue in experimental osteoporosis. -
Kidney damage is a common occurrence in patients with rheumatologic diseases and can develop either due to the disease itself or secondary to the drugs used in the treatment. The prevalence of renal damage and its severity depends on the underlying disease, as well as on the aggressiveness of therapy. For most rheumatologic diseases, kidney damage portends a poor prognosis and requires aggressive immunosuppressive treatment. Thus, it is important to diagnose and treat them early. On the other hand, it is almost impossible to group NSBNs according to the greater or lesser adverse effect on the kidney - there are very few comparative scientific studies. But it can be argued that practically all NSPS (including selective COX-2 inhibitors) have side effects on the kidneys. It is important to add that other pain relievers, such as acetaminophen (known to all as paracetamol), in some cases can cause kidney failure. -
The undoubted and justified interest of researchers in comorbid conditions in rheumatic diseases has not faded away in the last decade, but the concept of multimorbidity has not yet been integrated either into clinical practice or into scientific research in the field of rheumatology. Renal comorbidity is common in patients with rheumatic disease on the basis of regular examination of serum and urine renal function tests. When patients have both arthritis and kidney disease, the following questions should be addressed. Is kidney disease a complication of rheumatic disease or its treatment, or arc they both manifestations of the same systemic autoimmune disease? This article is intended to clarify the above issues and to be used by rheumatologists and nephrologists in the treatment and monitoring of these diseases.
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Improvement of methods of pre-operational preparation of scoliotic disease in ChildrenThe indications for the use of an optimized preoperative treatment and diagnostic complex for the preparation of paravertebral tissues and the contents of the spinal canal for radical correction in children with scoliotic disease of grade IV were determined. The proposed method extends the capabilities of a practical orthopedic-vertebrologist in assisting sick children with this disease.
Doctor's Herald -
Here are presented the results of conservative treatment of 199 patients wint congenital hip dislocation (hip dysplasia). After 30 years, the results of treatment has been studied in 102 patients. Good results were in 44 patients, satisfactory in 31 and unsatisfactory in 27 patients. The reasons for unsatisfactory results have been identified and methods of their prevention have been recommended. -
Purpose of the study: study and evaluation of biphosphonates in the treatment and prevention of perimenopau-sal osteoporosis. 60 perimenopausal patients were examined. In both groups, age are ranged from 45 to 55. The first group consisted of women who were offered alendronic acid dose of 70 mg per week for 6 months. The second group includes patients who, for economic reasons, did not take the above drug. The examined women determined the level of calcium and alkaline phosphates in the blood. The determination of bone mineral density was carried out using the ultrasonic densitometry method. From the above situation it is obvious that treatment with a group of biphosphonates, in particular alendronic acid 70 mg per week, significantly increases bone mineral density, which in turn prevents atraumatic fractures in women in the perimenopausal period. -
Analgetic efficiency and safety selective cyclooxygenase-2 inhibitor Etoricoxib (veroxib) in diseases of locomotor systemThe article provides data on the use of selective inhibitor cyclooxygenase-2 Etoricoxib (veroxib) in patients with rheumatoid arthritis, acute attack of gout Prenatal was applied in an ad dose in the complex therapy. The authors showed that Etoricoxib (Veroxib) already at dose of 90 mg 1 time a day as part of complex therapy has a pronounced anti-inflammatory and analgesic effect in patients with rheumatoid arthritis, while not only decrease in articular syndrome but also a decrease in inflammatory activity indicators, and at a dose of 120 milligrams 1 time a day as part of a complex therapy has a pronounced analgesic and anti-inflammatory act in patients with acute gout (WAG)
Doctor's Herald -
The effect of complex drug (anti-inflammatory, basic) and non-drug (physiotherapy, procedures of therapeutic gymnastics) therapy on clinical indicators in 80 patients with early osteoarthritis (OA) of the knee joints was studied. It has been established that complex treatment contributes to the effective abating of pain (according to VAS) and the improvement of the motor activity of the knee joint (according to the criteria of experts). At the end of inpatient treatment (10-12 day), the course of OA improves (according to the Lekcn index) and the risk of synovitis is reduced (according to the criteria of L.M. Noskova, 1987). -
The assessment of efficiency of calcium drugs on the basis of basic therapy of rheumatoid arthritisFor the purpose of studying the development of osteoporosis in rheumatoid arthritis (RA) and efficiency of using calcium drugs on the basis of treatment, there were examined 70 patients at the age from 40 to 67 years old who were ill with RA. For determination of the degree of osteoporosis and condition of density of bone tissue in the range of laboratory methods of researches were used "Inquirer of International fund about osteoporosis" and computerized X-Ray density. The results of research shows that the use of calcium drugs on the basis of basic treatment of patients with rheumatoid arthritis gives more positive effect on treatment of this kind of diseases
Journal problems of biology and medicine -
It is known that the existing methods of conservative treatment of dystrophic diseases (osteochondrosis) of the spine are aimed at improving the quality of life of patients by eliminating the main clinical symptom of this disease - pain syndrome. -
Current state of the problem of complicated damages of lumbar part of spineInjuries of the spine and spinal cord account for 0.7-4% of all injuries of the musculoskeletal system [2,6,8]. According to Simo-nova I.A. and Kondakova E.N. (2003) among all of skeletal injuries, about 6.0% are spinal injuries, of which about 30.0-40.0% of injuries are accompanied by neurological deficits. In Russia, annually 600-640 people per 10 million people receive mostly young young and able-bodied age spinal cord injuries, and 8000 people become disabled [11,16]. Over the past 70 years, spinal injuries have increased by more than 200 times, which is associated with urbanization, the development of production and transport [13,16,17].
Journal problems of biology and medicine -
Cardiovascular risk is a major problem in modem medicine in patients with rheumatoid arthritis. In these patients, prevention of cardiovascular diseases, identification of risk factors and prediction of cardiovascular risk arc of scientific and practical importance, thereby reducing morbidity, disability and mortality, as well as improving the quality and prognosis of patients. When determining the frequency of cardiovascular risk factors in patients with rheumatoid arthritis, it is important to identify indicators such as heredity, Smoking, rheumatoid factor, hypercholesterolemia, abdominal obesity and C-reactive protein. -
It was examined clinical features, data of joint syndrome, neurotic changes and the level of hormones in blood in 48 patients with rheumatoid arthritis (RA) (women - 32, men - 16) in the age from 60 to 73 years old (in average 69,5±2,2 years) and 40 patients (women - 31, men - 9) in the age from 16 to 59 years old. In patients older 60 years it was often determined the high level of the activity of the disease (according to DAS 28), significant deterioration of roentgenological signs and functional condition of the patients. For this disease it was typical more severe beginning, injures of the big joints such as knee joint, humeral and the ankle and the development of the significant component of exudation due to the asymmetric oligoarthritis. Most accompanying diseases were arterial hypertension (45,8%), ischemic heart disease (41,6%). The carried out research was promoted to reveal the neurotic disorders in 72,7% of patients: in 22,7% - weak, in 35,2% - moderate and in 14,8 % - high degrees of disorders. In group of the patients in the age of till 60 years old neurotic symptoms were revealed in 60,0 % of patients, and in group of the patients older than 60 years - in 83,3% of patients such symptoms were revealed in 1,4 times more often. In group of the patients older 60 years old the level thyrotrophin-releasing hormone (TRH), triiodothyronine, adrenocorticotrophic hormone (ACTH) and cortisol were authentic lower than in patients till 60 years old (P < 0,05 and P < 0,02), and the level thyroxine not always correlated with age and did not correspond to the level of TRH and triiodothyronine. -
Possibilities of radiation research methods for damages of soft woven structures of the knee jointDamage to the knee joint is a serious problem in clinical medicine, as it is a fairly common cause of disability and disability [4, 8, 21]. The knee joint is involved in the pathological process in a variety of diseases - deforming osteoarthritis, rheumatoid arthritis, seronegative spondyloarthritis, microcrystalline arthropathies, chondromatosis, injuries. Injuries of the knee joint occupy one of the first places among all cases of pathology of the musculoskeletal system, and from 43% to 80% of cases are injuries of its ligamentous apparatus [4, 5, 8]. Due to the peculiarities of the anatomical structure of the knee joint, its soft tissue structures are damaged more often than the bone components. Ligamentous apparatus injuries occupy the first place and account for up to 50% of injuries of the knee joint, up to 24% of injuries of the lower limb. Chronic injuries of cartilage, menisci, and cruciate ligaments, which are recorded with a frequency of up to 79%, are the cause of the development of degenerative-dystrophic changes in the knee joint [2]. Degenerative-inflammatory diseases of the joints are a common cause of persistent disability in the population of various age groups. Osteoarthritis is the most common joint disease, occurring in 10-20% of the adult population.
Journal problems of biology and medicine -
Features of hormonal status and mineral exchange in juvenile rheumatoid arthritis in children with different forms of the currentThis article presents the results of a comprehensive examination of 55 patients with juvenile rheumatoid arthritis. This type of children has desynchronization in the endocrine system, which is manifested in the increase of thyroid hormones, and the severity of the disturbances depends on the form, the expressed activity and the duration of the disease. There were changes in the parameters of the structural and functional state of bone tissue in children suffering from JRA, which manifested itself in the form of osteoporosis or osteopenia of varying severity.
Doctor's Herald -
Modern aspects of diagnostics and treatment of acute hematogenic osteomielitis in the bone of the tanged joint in childrenThe problem of acute hematogenous osteomyelitis (AHO) in children in practical healthcare remains relevant to this day, due to the high incidence rate, severity of the course, difficulties in early diagnosis, persistent high mortality, frequent transition of the disease into a chronic form with subsequent disability of children [2, 6, 20, 22].
Journal problems of biology and medicine -
In this article, the effects of therapeutic and gymnastic exercises on patients are studied and the results of the study are presented. 46 patients with osteochondrosis of the lumbar department were examined. The patients were divided into 2 groups. The results of the study showed that the application of therapeutic physical training to patients with osteochondrosis, improves the condition of patients, improves the motor activity and the quality of life of the patient, increases efficiency, helps improve the patient's fitness. -
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the development of symmetrical arthritis of peripheral joints, leading to progressive destruction of articular structures, as well as systemic damage to internal organs. ICD-10: M05-06. Epidemiology. The prevalence of the disease is about 1%. Women get RA 3 times more often. Most often, people aged 35-45 get sick. -
Based on the results of the study, the prevalence of low bone mineral density in patients with premature ovarian failure was determined. A complex assessment of the factors that play an important role in the reduction of BMD in patients with premature ovarian failure: the age factor and the level of sex hormones. -
Distribution and structure of risk factors of osteoporosis in postmenopausal women in Uzbekistan2329 women of 50 to 80 years of age, who were in menopause and lived in various regions of the Repub-lic. Prevalence of osteoporosis among surveyed postmenopausal residents comprised 33.4%, osteopenia -34.0%. The number of women with normal BMD significantly declines with the increase of age (86.2% at age of 50-59 years, to 1.3% - at ≥70 years). Nearly third of women (31.8%) regularly consumed dairy products, and slightly more than half (54.7%) lead an active lifestyle. Irregular consumption of dairy products, low phys-ical activity and the duration of menopause were the risk factors in the studied group of women
Journal problems of biology and medicine -
Efficiency of treatment of clinical and paraclinic manifestations of rheumatoid arthritisIn the study of 168 patients with rheumatoid arthritis, neurotic disorders (ND) were found in 65.6% of patients: 22.6% - weak, 31.7% - moderate and 14.9% - severe degree. The most frequently diagnosed asteno-vegetative disorders are 61.3%. In 24.4% of patients, asthenovegetative symptoms were combined with emo-tional symptoms, 14.3% had hypochondriacal symptoms, 9.5% had hysterical symptoms, and 4.8% had obses-sive disorders. With ND of an easy degree, complex treatment was performed with the use of restorative drugs, physiotherapy and physiotherapy procedures, medium degree - with sedatives (novopassit, sedavit, glycin, adaptol), expressed degree - with antidepressants. At the end of treatment (10-21 days) of all patients with ND in 66 (54.1%) was complete, 44 (36.1%) - a significant reduction in symptoms. In 12 (9.8%) patients, the symp-tomatology of ND did not improve. After the course of complex treatment in 11.5% of patients the result was assessed as unsatisfactory, 26.2% - satisfactory and 62.3% - positive. In the control group (46 patients without ND), these results were obtained respectively in 10.8, 37.0 and 52.2% of patients
Journal problems of biology and medicine -
Secondary osteoporosis (OP) is a serious complication in patients with rheumatoid arthritis (RA). From 28 to 77% of RA patients have ostcopcnic syndrome and osteoporosis. The most important risk factors for OP in RA include severe disease, the absence of remission in RA, prolonged inadequate therapy with glucocorticoids (GC), and early menopause. There is a direct dependence of the development of OP with a RA of more than 7-10 years. Despite the powerfol anti-inflammatory effect, HA accelerates the development of OP, fractures and patient disability, especially in the first 6 months, taking the drug.
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