All articles - Neuroscience and Neurology
Number of articles: 594
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Purpose of the study: to study the clinical symptoms, the level of depression and the quality of life in patients with IBS. Material and research method: a total of 121 patients and healthy people were examined. The patients IBS with intestinal manifestations were divided into 3 groups: IBSd (diarrhea) -51 patients (20 men and 31 women), IBSc (constipation) -66 patients (33 men and 33 women). IBSm (mixed) -4 patients (2 men and 2 women). Results: in the clinical variant of IBS with a predominance of diarrhea, the most intense abdominal pain syndrome was observed. With IBS with a predominance of diarrhea, deeper depressive changes are observed than IBS with a predominance of constipation and mixed type. -
Defects of childrens developments who were born from epilepsys disaeased parentsThe research task was to study developmental anomalies, stigma of diembriogenesis and various mal-formations in children whose parents took anti- epileptic drugs. The children were divided into subgroups ac-cording to the age, they underwent an anthropometric study, a clinical and neurological examination instru-mental analysis. It was found in the process of acquiring defects in children born from fathers with epilepsy
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Parameters of nervous conductivity associated with chronic pain syndrome in patients with interstitial cystitis and lumbalgia47 patients with chronic pain syndrome were examined on the outpatient setting: 17 with bladder pain syndrome / interstitial cystitis (BPS/IC), 30 with lumbalgia. Control group was made up of 15 healthy volun-teers. Pain syndrome was evaluated with the Visual Analogue Scale (VAS). Electroneurography of nerve su-ralis evaluated latency, amplitude and conductivity speed. Nociceptive flexor reflex (NFR) test evaluated pain threshold (PT), reflex threshold (RT) and PT/RT index. The obtained electroneurography data indicated ab-sence of any nerve suralis neuropathy in both groups. Significantly lower pain threshold rates in both BPS/IC and lumbalgia patients comparing to the control – testified presence of neuropathic pain component. No signif-icant difference of neurophysiological parameters found in both patient groups could specify similarity in path- ogenesis of chronic pain syndrome of different localization
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Surgical approach to the treatment for patients with traumatic intracranial hematomas in the acute period of severe craniocerebral trauma342 patients operated on for severe traumatic brain injury in Republican Specialized Scientific and Practical Medical Center of Neurosurgery from 2008 to 2017 were examined and treated.Decompressive cra-nioectomy was performed by 222 patients out of 342 (64,9%), Craniotomy - 120 (35,1%). Decompressive cra-niectomy was the main method of surgical treatment of patients with acute traumatic intracranial hematomas, accompanied by edema and prolapse of the brain. Reducing the time elapsed from the moment of trauma to surgery, correction of hemodynamic disorders, increased surgical efficiency, reduced the risk of complications in the postoperative period, and improved treatment outcomes
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Botulinum therapy in the complex rehabilitation of children with cerebrsl palsyThe research was based on the study of the conservative rehabilitation of children with cerebral palsy, us-ing botulinum therapy. Evaluation of treatment depended on the age of patients and the number of injections. No age difference in clinical and neurophysiological indicators was recorded. The positive effect of botulinum ther-apy is preserved in children who received 1 injection of Botulotoxinum as a reduction in muscle spasticity. An increase in the range of movements
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Clinic and psychopathological features of patients with chronic pain syndrome in diseases of the peripheral nervous systemPatients with peripheral nervous system disorders, including radiculopathy, plexopathy, compression-ischemic neuropathy, and chronic diabetic polyneuropathy were examined. Specific clinical signs of peripheral nervous system disease, electrophysiological signs of damage, neuroimaging signs of damage were used. Clini-cal and psychopathological studies show three options for psychophysiological disorders: asthenic, anxiety and depressive disorders.
Journal problems of biology and medicine -
From the first days of their lives, newborns experience primary pain due to neonatal screening, primary treatment and blood collection for laboratory analysis. As a result of untreated analgesia, the risk of developing neurological consequences is high and prevention is necessary. -
Change in cerebral hemodinamics in patients with discirculatory encephalopathy with intravenous ozone therapyThe aim of the study was to evaluate the effect of intravenous ozone therapy (OT) on the indices of cere-bral hemodynamics in patients with different stages of dyscirculatory encephalopathy. Patients are divided into groups: one of the groups on the background of traditional treatment received a course of OT. ОТ leads to an increase in anticoagulant activity, the linear velocity of blood flow along the common carotid artery and along the internal carotid artery by means of ultrasound dopplerography was reliably normalized, the indices on the main arteries of the head on the extracranial level were normalized
Journal problems of biology and medicine -
Bioelektric activity of the brain in children with consequences of perinatal injuries of the central nervou systemThe bioelectrical activity and its changes on the EEG have been studied, which reflect the severity of functional disorders and are manifested by various pathological phenomena, the correct interpretation of which allows one to assess the degree of functional disorders of the central nervous system
Journal problems of biology and medicine -
The degree of perivascular and pericellular edema In the cerebral hemispheres of persons who died from acute massive blood lossThe analysis of the state of perivascular and pericellular edema in the brain of people upon death from massive blood loss was carried out. It is established that the thanatogenesis of blood loss varies depending on the type of damaged vessels, as well as the frequency of injuries. With massive blood loss caused by single and especially multiple damage to the heart and great vessels, as well as multiple damage to peripheral vessels in the thanatogenesis. neuronal damage predominates. With a single lesion of peripheral vessels in thanatogenesis with massive blood loss, the role of the vascular component of the brain increases.
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Frequensy of cognitive and non- cognitive disturbances in patients with young age with chronic cerebrovaslar diseases with conditioned arterial hypos and hypertensionCerebrovacular diseases can for a long time only be manifested by cognitive impairment. More than 1/3 of the examinations revealed discirculatory encephalopathy of the 1 st stage, mild and moderate cognitive im-pairment appeared in the first and second stages of discirculatory encephalopathy (DE). Symptoms of anxiety in patients with chronic cerebrovascular pathology in 92,8% of cases were observed in stage II stage discircu-latory encephalopathy due to arterial hypertension and in 89,6% with second stage discirculatory encephalo-pathy due to essential arterial hypertension(EAG)
Journal problems of biology and medicine -
Results of clinical-neurological and electroneyromyografy surgery of patients with vascular parkinsonismThe peculiarity of the clinical course of Parkinsonism in patients with acute impairment of cerebral cir-culation was studied. We observed 58 patients with vascular Parkinsonism (VP) who underwent ischemic stroke, aged from 40 to 56 years. Patients were under our supervision for 20 days, who underwent clinical and neurological examination, ENMG, and also vegetative sphere research. Electroneyromyografy signs are early VP criteria, in the absence of clearly defined symptoms, and are manifested in the form of an increase in the rate of impulse conduction along efferent and afferent fibers
Journal problems of biology and medicine -
Comparative characteristics of the neurological symptoms in children de- Pending on type of delivery85 newborns bom with the help of different types of delivery were examined, it was revealed that in case of emergency caesarean section, the highest frequency of neonatal ma (adaptation to extrautcrinc life was observed, w'hich was accompanied by a large number of cases of perinatal Central nervous system damage.
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The results of a neuropsychological study of patients with chronic cerebral circulatory insufficiency and hypothyroidismAnnotation: One of the significant risk factors for cerebrovascular diseases are endocrinopathies. We examined 120 patients with chronic cerebral circulatory insufficiency (CNMI) suffering from hypothyroidism. The results of a neuropsychological study revealed that HNMK with hypothyroidism proceeds with more pro- nounced cognitive disorders (memory, praxis, gnosis), they are combined with severe emotional-volitional dis-orders in the form of asthenic, anxious and depressive disorders
Journal problems of biology and medicine -
The use of l-karnitin in newborn infants with perinatal hypoxic lesions of the central nervous systemIn the light of scientific research, a deficiency of carnitine is observed in newborn children, which leads to disruption of the process of fatty acid transfer into the mitochondria. In groups of children from 60 newborns with various pathologies of the central nervous system (CNS), carnitine was included in the treatment; on the basis of clinical laboratory and instrumental methods of research, positive dynamics was established at a faster time with the restoration of normal activity of mitochondria succinate dehydrogenase (SDH) and alpha glycer- ophosphate dehydrogenase (αGDPH).
Journal problems of biology and medicine -
Place of cerebroprotection in the prevention and correction of postoperative cognitive dysfunction during surgical interventions in elderly patientsThe article presents the results of a study of 120 patients aged 60-75 years, prepared for a planned surgical intervention. Depending on the method of drug preparation, all patients were divided into 2 groups: patients of the I-st (main) group received medical preparation as follows: 3 days before the operation, 500 mg of citicoline was administered i.v. in a jet in the morning and evening, 10 ml of thiocetam, previously diluted in a 0.9% solution of sodium chloride intravenously driply, once a day; cerebroprotection was not performed in patients of the second (control) group. The results of the study suggest that prcopcrativc ccrcbroprotcction docs not affect the need for anesthetic, significantly improves the period of post-anesthetic rehabilitation and prevents the development of cognitive deficit in the early postoperative period in elderly patients operated on in conditions of ketamine and fentanyl with ALV.
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Characteristics of heart rate variability in children with spastic forms of infantile cerebral palsyThe article estimates character and variability of the rhythm of the heart in children with spastic forms of infantile cerebral. All the groups of children surveyed by means of a computer program measured heart rate variability, which will allow to evaluate compensatory and adaptive capabilities and dynamics of the child's rehabilitation potential. According to the study of HRV in children with cerebral palsy, signs of autonomic dys-function and a decrease in the body's adaptive reserves are determined in the form of a decrease in the overall functional state.
Journal problems of biology and medicine -
Clinical analysis of vertigo in patients with cochleovestibular disordersThe article contains results of clinical analysis of different variant dizzinesses. The article presents mod- ern data concerning clinical manifestations, diagnostic approaches in cases resulted from the most frequent causes of the central vertigo, peripheral vertigo and dizziness. Analysis of the results of clinical and psycholog- ical methods used revealed that along with diagnostic conversation for more complete data for dealing with diagnosis features psychosomatic health status of patients with dizziness, it is necessary to apply standardized psychometric scale and specialized vestibular questionnaires, in particular VRBQ
Journal problems of biology and medicine -
Clinical-neurological examination and the results of neuroimaging of children with the consequences of craniocerebral traumaMRT date are presented for the study of children with craniocerebral trauma, in the initial and long-term period, depending on the clinical picture, paresis (hemiparesis, tetraparesis and so on). The obtained results of both diffuse and focal posttraumatic disorders in the central nervous system in patients with consequences of a moderate craniocerebral trauma
Journal problems of biology and medicine -
Author presented evaluation data of the computer brain neurosonography results and hemodynamic monitoring of the 56 newborns with hemorrhagic insult. At newborns with hemorrhagic insult were identified significant changes of the hemodynamic not only in the brain, but also of the whole organism, which is not always manifested in the clinical symptoms. It must be taken into account when treating newborns with hemorrhagic insult, especially during surgical interventions. -
Intellectual development of children with progressive muscular dystrophies of duchenne beckerThis article provides data on the evaluation of the intellectual development of children with progressive muscular dystrophy Duchenne / Beccre. It is established that 43% of children have intellectual insufficiency. The lower level of non-verbal intelligence, reduced ability for visual analysis and synthesis, intellectual exhaus- tion, low level of arbitrary control, difficulty in distributing attention and general infantilism in children with progressive muscular dystrophy of Duchesne came to the fore in the study. While in children with Becker's pro- gressive muscular dystrophy, intelligence corresponded to the age norm.
Journal problems of biology and medicine -
Frequency and features of epileptiformed anomalies of eeg in children born from parents of epilepsia patientsThe study included children whose parents had epilepsy. They were divided into groups: children from mothers with epilepsy and children from fathers with epilepsy. Patients were divided by age. EEG video was monitored. The result was epileptiform anomalies in the EEG children born from parents with epilepsy are sig-nificantly more likely than children with idiopathic epilepsy. There were no differences between children born separately from mothers and fathers with epilepsy.
Journal problems of biology and medicine -
Frequency and structure of visual impairment in children with epilepsyThis article reflects the frequency and structure of visual disorders in children with epilepsy. The study is based on data from a clinical ophthalmological examination of the eyes in 151 children with epilepsy. In the course of the survey, it was found that the frequency of occurrence of the pathology of the eyes was 68.2%. The most common pathology of eyesight in children with epilepsy is established at the age of 1 year to 5 years, which is 47.5%. The correlation interrelation between the duration of the disease and the frequency of epileptic seizures on the development of the pathology of the organs of vision was proved.
Journal problems of biology and medicine -
The value of tethering syndrome in the pathogenesis of pain in patients with lumbar osteochondrosisThe goal is to determine the value of tethering syndrome in the development of pain in patients with lumbar osteochondrosis. Materials and research methods: The study was conducted in 112 (61 men, 51 women) patients operated on for lumbar osteochondrosis with lumbar ischialgic syndrome. Conclusion: Tethering syndrome (terminal thread tension syndrome) developing due to cauditis (terminal cistern of the spinal cord) is the cause of compression and traction (damaged-demyelinated) hyperalgesic nerve root with subsequent development of radicular pain syndrome.
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Gender features of risk factors and background diseases at different types of ischemic stroke in elderly and senior personsGender differences of risk factors and background diseases in elderly and senile patients with ischemic stroke have been established. So it was established that the proportion stroke of hemodynamic and lacunar stroke was reduced in the elderly due to an increase in the percentage of patients with athcrothrombotic stroke both among female and among men. Risk factors for ischemic stroke also have their own characteristics and differed according to age and gender. Taking into account the heterogeneity of stroke, in people aged 44-59 years, revealed the highest percentage of smoking (p<0,05) factors, dyslipidemia (p<0,05) and psycho-emotional stress(p<0,05). In elderly and senile patients, the smoking factor (p<0,05), is significantly reduced. In individuals aged 44-59 years, there was a significant predominance of atherosclerorosis, arterial hypertension, coronary heart disease, TIA, rheumatism in men, and also diabetes and heart rhythm disorders in women (p<0,05),. At the same time, in patients with men of senile age, the prevalence of the proportion of CHD and TIA in the background disease structure prevailed (p<0,05).
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