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View No. 1 (107) (2019)

No. 1 (107) (2019) Problems of biology and medicine

Journal: Journal problems of biology and medicine

Published: 2019-03-14

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Статьи

Development of algorithms endoscopic treatment of patients with ipsilateral kidney and ureter stones A comprehensive examination and treatment of 146 patients with ipsilateral kidney and ureter stones was performed. Results: the use of the endoscopic treatment algorithm for patients with ipsilateral kidney and ureteral stones allowed increasing the degree of stone getting to 87.9%, the duration of operations was 75.3 ± 2.6 minutes, the frequency of intraoperative complications was 2.1 ± 1.2% , the average length of stay of patients in the hospital is 6.2 ± 0.4 bed-days. The inclusion in the complex of therapeutic measures of the developed algorithm of endoscopic treatment of patients with ipsilateral kidney and ureter stones allows to increase the effectiveness of treatment of patients with nephrolithiasis

D Mirkhamidov, F Akilov, Sh Mukhtarov, F Nasirov, S Kasimov

58-62
218 18
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Parameters of nervous conductivity associated with chronic pain syndrome in patients with interstitial cystitis and lumbalgia 47 patients with chronic pain syndrome were examined on the outpatient setting: 17 with bladder pain syndrome / interstitial cystitis (BPS/IC), 30 with lumbalgia. Control group was made up of 15 healthy volun-teers. Pain syndrome was evaluated with the Visual Analogue Scale (VAS). Electroneurography of nerve su-ralis evaluated latency, amplitude and conductivity speed. Nociceptive flexor reflex (NFR) test evaluated pain threshold (PT), reflex threshold (RT) and PT/RT index. The obtained electroneurography data indicated ab-sence of any nerve suralis neuropathy in both groups. Significantly lower pain threshold rates in both BPS/IC and lumbalgia patients comparing to the control – testified presence of neuropathic pain component. No signif-icant difference of neurophysiological parameters found in both patient groups could specify similarity in path- ogenesis of chronic pain syndrome of different localization

A Fedoruk, М Stepanchenko, V Romanenko, О Vovk

97-101
200 28
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Possibilities of ultrasound examination of the thyroid gland in children of adolescents in Tashkent In order to study the possibility of early detection of thyroid disease in children using ultrasound, a pre-ventive examination was conducted of 169 schoolchildren, students in grades 5 and 9 of four schools in the Mirzo-Ulugbek district of Tashkent. The results of a survey of adolescents showed that in 153 children, the echographic picture of the thyroid gland corresponded to the age characteristics. The volume of thyroid in children was within the normal range. However, 4 (2.4%) children had colloidal nodes, and colloidal cysts - 12 (7.1%) children. No child had clinical manifestations of dysfunction of the gland. The high frequency of detec-tion of these formations in the older group of children seems to be associated with the acceleration of growth processes. The highest percentage of thyroid gland colloid formations in boys 15–16 years of age corresponds to the active stage of sexual development. Adolescent children are recommended to conduct an ultrasound ex-amination of the thyroid gland for the early detection and prevention of diseases

A Fazylov, I Shamansurova

95-96
291 27
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Improvement of methods of pre-operational preparation of scoliotic disease in children Indications Application optymyzyrovannoho preoperative medical- diagnostically complex for the train-ing of paravertebral tissues and contents of the spinal canal k radykalnoy correction in children co skolyoty-cheskoy illness IV degree. Predlahaemыy method of rasshyryaet abilities Almost orthopedic vertebrologist As-sist in aid to children with data disease

F Umarkhojaev, M Iskandarov

91-94
167 20
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Defects of childrens developments who were born from epilepsys disaeased parents The research task was to study developmental anomalies, stigma of diembriogenesis and various mal-formations in children whose parents took anti- epileptic drugs. The children were divided into subgroups ac-cording to the age, they underwent an anthropometric study, a clinical and neurological examination instru-mental analysis. It was found in the process of acquiring defects in children born from fathers with epilepsy

I Toshtemirova, A Jurabekova, О Ravshanov, Sh Boltaeva

88-90
360 30
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Efficiency of diagnostic algorithm in children with chronic glomerulonephritis with atopic dermatitis Surveyed 145 children aged 7 to 11 years. Of them: with nephrotic form CGN - 40; CGN on the back-ground of AD-40; AD-40. The control group consisted of -25 healthy children. It was found that in children with nephrotic form of CGN with blood pressure, CGN has a high information content of qualitative and quan-titative signs: oliguria, proteinuria, type 3 diabetes; CGN + BP: edema, total protein, ASL to kidney tissue, CIC; by markers of skin pruritus, IgE. As a diagnostic criterion for the nephrotic form of CGN with AD, there are immunopathological signs: an increase in the renal ASL, CIC, IgE, and overproduction of IL2, IL4. The effectiveness of the use of the diagnostic algorithm in CGN: early detection of GNSS- 35%, HVIN- 65%; CGN + AD: GRNS- 45%, GZNS 55%; AD 20%.

L Rakhmanova, U Karimova, A Samadov

84-87
273 24
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Causes of culture distribution after amputation at the level of the crus and the way of their prevention in patients with diabetes mellitus in critical ischemia of the lower limbs The data of transcutaneous oximetry (tpcO2) and microflora from biomaterial taken from muscle tissue m were studied. Soleus amputated limbs due to critical ischemia of the lower limb severe. The results of the study showed that in patients operated on for severe ischemia of the lower limb of a severe degree, the level of tissue hypoxia in terms of tpcO2 was directly proportional to the clinical picture of the disease. During opera-tions at the level of the tibia, according to Mitish, it is necessary to determine the data of transcutaneous oxi-metry (tpcO2) and microflora, to make bacteriological seeding from the soleus muscle tissue, in order to de-termine further targeted treatment

A Rakhimov

79-83
512 30
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Some indicators of phosphorous-calcium exchanges and general condition in children with tubulo-interstitial kidney diseases 48 children with secondary pyelonephritis and oxalate nephropathy were studied. A violation of calcium and phosphorus metabolism was revealed. It depended on the presence of risk factors, among which the patho-logical course of pregnancy in the mother, postponed rickets, deficiency of alimentary calcium, and hypodyna-mia are of the greatest importance

Sh Pirmanova, B Yuldashev, Sh Nazhimov

76-78
292 27
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Verebral pain syndrome in children According to literary research, vertebral pain syndromes (VPS) vary in a very wide range from 8 to 74%. The aim of our study was to determine the therapeutic tactics for children with VPS, which is different from adult practice. Evaluation of the effectiveness of therapy was monitored on scales. The complex treatment which is adapted to the age of children gives positive results in the form of reduction and relief of pain

X Ochilov, A Jurabekova, D Kholmurodov, S Rajabov Rajabov, N Vyazikova

73-75
249 26
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Results of clinical and neurological examination and treatment of children with cerebral palsy Surveyerd children with cerebral palsy. The division was according to the forms of the disease and de-pending on the treatment received. Traditional treatment included all previously known medical and physio-therapeutic procedures. The results indicated that the traditional treatment was insufficiently effective, which was determined by the persistence of a high frequency of motor disorders and necessitated the use of more ef-fective rehabilitation methods

Sh Normatova, A Jurabekova, G Niyozov, F Fayzimurodov

70-72
360 29
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Diagnostic meaningfulness of cochleobestibular violations for patients with illness of meniere 23 patients were plugged in research, suffering БМ with the hemilesion of internal ear. In a interap-proachable period a voice-frequency threshold audiometry, video-nystagmography, caloric test, videoimpulsive test, was conducted all patients. For БМ absence of the hidden spontaneous nystagmus is most characteristic, however the positive test of shaking of head can register oneself. The presence of asymmetry of results of calor- ic test and normal values of data of videoimpulsive dough are also characteristic in period. At the analysis of character of decline of rumor and coefficient of asymmetry in the labyrinth (CASTLE) revealed a tendency to increase hearing thresholds with increasing CASTLE

M Nasretdinova, X Karabaev

66-69
298 31
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Features of cerebral hemodynamics and concentration of neuron-specific enolase in the expert assessment of traumatic brain injury in children and adolescents This work describes results of studying of neurologic status, cerebral hemodynamic and concentration of neurospecific Enolase as a marker of injury of neural tissue in children during expert assessment of cranio- cerebral injury. Were examinated 68 children from 8 to 18 years old , who were treated in the department of traumatology, orthopedics and neurosurgery of TashPMI. It was established that improving the accuracy of forensic medical diagnostics in children of different ages with СBI, it is advisable to include assessment crite- ria in determining the severity of injury to age-dependent features of cerebral hemodynamics and neurospecific Enolase concentration.

Zh Musurmonkulov, N Nuritov

63-65
230 37
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Hemodynamic disturbances at chronic ischemia of the brain of hypertensive genesis The greatest changes by us were revealed at patients with the arterial hypertension (AH) of the III de-gree. At patients with chronic ischemia (CHEMICAL) hypertensive genesis of the MRT-research showed exist-ence of the diffusion merging large sizes of the centers of defeat whereas for chemical atherosclerotic genesis they had local character, and the centers were the smaller sizes

N Abzalova, D Usmanova

8-9
176 28
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Menopausal metabolic syndrome basis of cardiovascular risk Studying of components of a metabolic syndrome at women in a menopause, will allow estimating preva-lence, a pathogeny of development of MS, at early stages of its forming and considering influence of the andro-genic status timely to appoint hormonal correction, for reduction of risk of metabolic "adverse" visceral obesity and to carry out prevention of cardiovascular complications

N Mirzakhmedova

55-57
150 23
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Radiative diagnostics of exogenous allergic alveolitis The data of clinical, laboratory and X-ray studies of patients with exogenous-allergic alveolitis (EAA) induced by fungi of the genus Paecilomyces were analyzed. Radiographic changes were distinguished by poly-morphism and had a diffuse spread, changes in the transparency of the lung tissue, deformation of the pulmo-nary pattern of a mesh-cellular nature, formation of focal shadow-like shadows were determined. Three vari-ants of structural changes were observed: emphysematous – interstitial, parenchymal – interstitial, and pneu-monic (granulomatous). Changes in lung tissue density of the parenchyma, detected by CT, serve as an addi-tional diagnostic test in the early stages of EAA, when the information content of the conventional X-ray meth-od is limited, and densitometrically calculated changes in optical densities of lungs on CT can not be assessed visually by standard radiographs. Dedicated symptom complexes of radiology studies are pathognomotic for EAA of any etiology. Final verification of the diagnosis requires mycological examination and culture of the fungus in nutrient media.

G Mardieva

50-54
159 21
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Peculiarities of functional characteristics of patients with myocardial infarction and vascular comorbidity of cerebral localization The purpose of the given research was to analyze the relationship between the vascular comorbidity of cerebral localization, including acute cerebral circulatory disorders and / or transient ischemic attack in past history, and functional parameters of patients with myocardial infarction. The study has showed the presence of a direct reliable relation between the incidence of comorbid pathology of cerebral localization and parox- ysmal atrial fibrillation, as well as the presence of supraventricular arrhythmias. The necessity of developing differentiated individual rehabilitation programs in patients with myocardial infarction in combination with cerebral vascular pathology has been substantiated

L Levitskaya

45-49
99 19
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Comparative evaluation of the pre-stroke forms of cerebrovascular pathology in young persons This article presents the data of a comparative analysis of the clinical symptoms of the pre-stroke forms of cerebrovascular pathology on the background of hypertensive disease. It was found that a significant pro- portion of young patients have a clinical manifestation of the CVP on the background of HD. The development of CVP on the background of HD does not depend on the duration of the disease, but largely depends on the severity of the etiological vascular disease and the level of blood pressure. Patients with hypertension fall into the field of the view of neurologists later, and therefore, the available cardiovascular manifestations underes- timated, causing the performance of treatment of CVP with some delay and the risk of stroke is also increased

O Kim

42-44
251 35
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Comprehensive assessment of postural control in stabilometric study The paper presents data on the features of the manifestation of the syndrome of falls in patients 65-74 years. Since it is known that from 50 to 70 % of all falls in the elderly and senile age occur during walking, we conducted a comparative analysis of the parameters of walking in patients with and without falling syndrome. Estimation of parameters of the walk was carried out with the help of computerized stabilometric complex "Smart Equitest Balance Manager". The decrease in adaptive abilities to complex motor acts in elderly women with fall syndrome was revealed. In addition, a significant change in the indicators "reversal time" and "fluctu- ation in the reversal" of the test "Rapid reversal" in women 65-74 years of fall syndrome, which indicates a decrease in visual and vestibular information in balance control, deterioration of neurophysiological mecha- nisms and dysfunction of the musculoskeletal system

X Karabaev, M Nasretdinova

39-41
230 22
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Variants of the clinical course of the effects of perinatal hypoxic lesions of the central nervous system The objective of this study was to identify variants of the clinical course of central nervous system thera- py. The examined children were divided into groups with coarse focal lesions such as cerebral palsy and chil- dren with elevated functional impairment and minimal brain dysfunction. All children underwent a clinical and neurological examination of the neurophysiological EEG, TCDG. Identified brain immaturity, epileptiform ac- tivity, reduced blood flow to the vessels of the carotid pool

L Igamova, S Igamova, A Jurabekova, F Khalikova

35-38
354 28
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Autotransplantation of sounds 12 patients without somatic diseases were examined: 8 women and 4 men, aged 23 to 30, residents of Ternopil town. Using clinical and radiological methods of examination, they had found by ones periodontitis tooth that was not subject to therapeutic treatment, the presence of intact third molars. Autotransplantation and clinical observations were performed on 6 patients. According to clinical and radiological examination data, autotransplantation in patients, as a surgical method of treatment, is sufficiently effective. Clinical observations have proven that one way to restore the integrity of the tooth range can be autotransplantation. For its conduct, indications for surgical treatment with the use of modern diagnostic methods should be determined, patients' consent is required. To conduct autotransplantation should begin with indications for its implementation: the presence of intact third molars; presence of the first molars not subject to conservative treatment; age of the patient; health status; good hygiene of the oral cavity; preliminary careful X-ray examination. Autotransplan- tation of the third molar as a surgical method of treatment is a sufficiently effective, accessible, cost-effective operation for patients in the absence of the first molar

N Gutor

30-34
163 24
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Comparative study of evaluation methods of the thrombus for biosealants formation The use of new forms of biosealants based on thrombus is perspective direction in medicine. Thrombus may be studied from the view point of natural policompositive biomaterial without any negative influence on the organism. Especially retractive thrombi faced these requirements. In connection with this fact methods of evaluation and investigation of thrombus retraction, the study of their physic-mechanical properties have been had large significance. Current research was performed with aim to compare exist indirect methods of throm- bus retraction evaluation with perspective direct methods that allow assess physic-mechanical properties of thrombi. The work was performed in cooperation with researchers of Physic-technical institute at Academy of Science RUz.

A Voronin, N Dzhumaeva, O Kim, M Yusupov, R Sadykov, R Kabulov

26-29
193 34
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Erythrocytes and microcirculation of the oral mucosa when using laser and led radiation To study the form of red blood cells in prosthetic stomatitis and the dynamics of their changes in the course of treatment, peripheral blood was studied in 32 patients with prosthetic stomatitis and in 8 healthy do-nors. The calculations showed that the proportion of D in the peripheral blood obtained from the finger, is normally 89%, erythrocytes with a crest and echinocytes 8%, stomatocytes 2%, irreversible forms of erythro-cytes - 1%. The use of laser and LED technologies in dentistry in complex diagnostics and treatment is effective and promising.

I Baibekov, M Irkhanov

21-25
166 37
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Determination of reserves to reduce the frequency of cesarean section in the perinatal center using the Robson classification This study was performed in Republican Perinatal Center in Uzbekistan, from January 1, 2017 to De-cember 31, 2017. All women delivered during this period were classified according to the Robson classification consisting of 10 groups using their maternal characteristics and obstetric history. There were 5551 births, of which 1966 - from cesarean section. Robson's classification made it possible to determine the dynamics and reserves to reduce the caesarean section in the perinatal center: to increase vaginal birth after cesarean, vaginal birth at breech presentations, use a partograph to make a decision for the diagnosis of obstructive labor, suggest external cephalic version at breech presentation, develop a guideline on obstetric tactics in pregnant women with cardiac arrhythmias.

Sh Babazhanova, N Lubcic, S Bayramov

17-20
198 36
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Development of algorithms for performing tubeless and totally tubeless percutaneous nephrolithotomy in patients with nephrolithiasis A comprehensive examination and treatment of 345 patients with stones of the upper urinary tract. The use of the drainage-free and completely drainage-free PNL algorithm allowed 51.9% of the operated patients to perform the drainage-free PNL, and for 38.8%, the completely drainless PNL. As a result, the frequency of the catheter-associated BMI decreased, respectively, by 5.2% and 14.4%. The inclusion in the complex of ther- apeutic measures of the developed algorithm for performing a drainage-free and completely drainage-free PNL allows optimizing the tactics of endoscopic nephrolithiasis surgery and increasing the clinical efficacy of treatment

F Akilov, Sh Mukhtarov, F Nasirov, D Mirkhamidov, Y Safaev

13-16
192 19
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Статьи

Formation of osteoblastic cell differon Thanks to modern methods of studying cell biology, deepening the understanding of blood stem cells and connective tissue, knowledge of their origin and differentiation has been significantly enriched. However, despite this, they require systematization and understanding, taking into account theoretical provisions on histogenetic series, or cellular differons, and the development of modern criteria for differon [1, 3, 6].

A Yuldashev , A Makhmurov, M Yuldasheva

198-201
130 23
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