All articles - Respiratory System
Number of articles: 472
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Prognostic evaluation of the risk of chronic pathologies among tubcontacts of children in educational institutions sanatoriumThe method of questionnaire survey of parents to study the characteristics of regime moments and conditions of education in 1175 of children in preschool tuberculosis sanatorium profile - the main group ( 220 children) and in preschool general types - the control group (955 children). Number of children in the study group with the breastfeeding duration of 12 months or more was 1,8 times less than in the control group; the number of children in the main group 1,1 times more educated in beshik, and those children with the period of stay from 1,5 to 2 years were 1,3 times more. On average, 60% of children received the information about the elements of a healthy lifestyle in the family, 32% - in the preschool education and 8,5% - as a result of watching television, using the Internet and children's publications. Almost 70% of the duration of outdoor exercise, diurnal sleep, watch TV and play on the computer of preschool chil- dren exceded hygienic standards. The increase in the risk of chronic disease in children tubcontacts consistently influenced by factors such as the duration of the games on your computer, feeding children breast milk, watching TV, outdoor activities and education of the child in beshik
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Predicting the likelihood of myocarditis in patients with acute pneumoniaDue to the developed criteria to determine the likelihood of myocarditis in infants with pneumonia, made possible the formation of high-risk groups for adverse outcome of pneumonia. This will increase the likelihood of the development of myocarditis in children and the effectiveness of the therapy, to reduce the incidence of morbidity of acute pneumonia and significantly reduce the number of complications, and thus mortality rate
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Modern methods of treatment in children with chronic respiratory diseases pneumoniaThe usage of endobronchial autotransplantation of macrofagle cells of respiratory tract with poliox-idoniym, UFI, ozon fluid, lazer stimulation in children with chronic pneumonia positively influencedon the flow of inflammatory process in bronchus, that is has been confirmed by improvement of leukocyte index of intoxica-tion, endoscopic picture and cytologic bronchoalveolar – lavash fluid
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By the purpose of work was the comparison of clinical efficiency bronchodilatation at children of early age. Carried out analyzing of clinical results at 48 patients. The received results have shown, that at the patients 1st of group (24) applications Salbutamol promoted faster reduction of tachiapnea, improvement of a common condition of the patient, reduction of cyanosis at nose lips triangle and cough, disappearance of bronchobstruction symptoms. Whereas at 2nd group (24) of children receiving euphillin positive dynamic is marked in later terms and in small quantity of the patients. For 2-3 days of treatment the patients with auphilin купирование обструкции it was marked only at 66, 6 % of the patients, at application Salbutamol the complete removal bronchobstruction was marked at 91 % of the patients. Thus, a good transforming of patient and the fast improvement of a clinical status of the patients, prove advantage assignment of Salbutamol of bronchobstruction treatment. -
The role of inflammation in prolonged hyperbilirubinemii of newbornsAll newborns underwent standard laboratory and instrumental examination. Ultrasound examinations (brain, heart, abdominal organs), according to indications, electroencephalography was performed. In the presence of hypoxemia and mixed acidosis of newborns with respiratory distress syndrome, the use of spontaneous breathing with SDPPD improved the overall condition of newborns. This was confirmed by an improvement in the clinical and laboratory and radiographic data of each newborn. Spontaneous breathing with SDPPD is a technically simple and effective method of correction of hypoxemia in the syndrome of respiratory disorders
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Comprehensive treatment of patients with nose papillos and primary casesThe analysis of the effectiveness of complex treatment of 66 patients with papillomas of the nose and pa-ranasal sinuses was carried out. In the main group of patients, traditional therapy was supplemented by inges-tion of tyloron (Lavomax) according to the scheme and topical application of Viferon ointment. Immunological studies, as well as data of subjective evaluation, revealed high results in patients of the main group. The con-clusion is made about the possibility of using the preparation of Tyloron (Lavomax) and topically Vifeiron ointment in the complex treatment of nasal and sinus papillomas.
Journal problems of biology and medicine -
Endobronkhial therapy in treatment of complex therapy at patients with the thermoinhalation traumaThe analysis of results of treatment of 188 victims with the severe burn injury complicated by thermoin-halation damage of airways which were divided into the main and control groups is carried out. In the main group the programmed sanatsionny fibrobronkhoskopiya from the first hours from hospitalization with a fre-quency of 2-3 times per day depending on weight of thermoinhalation defeat during the necessary period of time were applied. In control group sanatsionny bronkhoskopiya were carried out irregularly, generally on request of the attending physician. Other treatment was identical in both groups. Active application the sanatsionnykh of bronkhoskopiya allowed to reduce statistically significantly the frequency of a purulent trakheobronkhit from 38,1% in control group to 14,0% - in the main group and to reduce a lethality from 93,5% in control group to 68,4% - basically.
Journal problems of biology and medicine -
Dynamics of indicators of thyroid function in children with asthmaThe degree of the effect of thyroid hormones (TG) metabolism in general, and asthma. Our results allow to predict the development of distireoza with a tendency to decrease thyroid hormone production in patients with bronchial asthma (BA) even in the absence of clinical symptoms of hypothyroidism
Journal problems of biology and medicine -
Hyperplasia of pulmonary endocrinocytes in children with pneumoniaIn the lungs, of children in early age, with inflammatory pathology, endocrine structures are detected with more regularity and their number is large. As longer the duration of the disease, more apudocytes and neuroepithelial bodies are found in the bronchi and the respiratory part. Inflammatory lung diseases in early postnatal ontogenesis are a predisposing factor for hyperplasia of apudocytes
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Bronchial obstruction in infants: prevalence, clinical manifestations, diagnosis and treatmentBroncho-obstructive syndrome is an urgent problem in pediatrics and occupies one of the first places in the structure of respiratory diseases in young children [1,3,5,10,20]. This is due to the wide prevalence of biofeedback in the general structure of bronchopulmonary diseases, severe course and complications. In children of the first years of life, up to 30-50% of acute respiratory infections are complicated by BOS, the main cause of which is acute obstructive bronchitis (AOB) [2,9,11,21]. Most diseases of the bronchopulmonary system occur with biofeedback, among which should be noted congenital and hereditary pathology of the respiratory system, malformations of the bronchi, respiratory distress syndrome, primary immunodeficiency states, aspira- foreign bodies, perinatal pathology, gastroesophageal reflux, increased intrathoracic lymph nodes, thymus hyperplasia, tumors, etc. [2,3,24]. The uniformity of clinical symptoms of bronchial obstruction in these diseases complicates early diagnosis and treatment tactics, which can lead to a protracted and recurrent course of some of them.
Journal problems of biology and medicine -
Metods of diagnosis and treatment hemangioms of nasal cavity and paranasal sinusesThe number of patients with benign neoplasms of the nasal cavity (PN) and paranasal sinuses (SNP) has recently been increasing and amounts to 8-10% of all neoplasms of the head and neck, and, as a rule, they are diagnosed late, taking them for various others, usually inflammatory diseases, due to which the majority of patients (70-90%) come to the clinic with an already widespread tumor process. Vascular tumors of the upper respiratory tract occupy the first place among benign neoplasms in this area in terms of frequency of cases; the mucous membrane of the nasal cavity is most often affected (78%). Hemangiomas are more common in females. This suggests that sex hormones are important in the genesis of vascular tumors. According to the WHO international histological classification, hemangiomas are divided into the following types: capillary, cavernous and venous. The color of the hemangioma depends on its histological structure; the capillary hemangioma is light red in color with clear contours and a smooth surface. Cavernous and venous hemangiomas differ in different shades of blue. Their surface is bumpy, and the contours are not clear
Journal problems of biology and medicine -
Republican Specialized Scientific-Practical Medical Center of Surgery named of academician V.Vakhidov The results of examination and treatment of 327 patients with postoperative intrapleural complications operated in CTS at the Regional Clinical Hospital № 1 named after S.V. Ochapovsky (Krasnodar) and in the Department of Surgery of the lungs and mediastinum RSCS named after acad. V.Vahidov.The authors have identified certain risk factors for postoperative intrapleural complications and developed specific directions on the possibilities of prevention and treatment. The frequency of development of intrapleural complications in groups of patients operated on before and after 2006 y. was analysed. In general, the introduction of complex treatment and prevention of specific measures for the prevention of postoperative intrapleural complications, including nebulizer therapy and low intensive laser therapy at all stages of treatment, intraoperative use of caustic argon to ensure adequate hemostasis and early connection of centralized or individual active aspiration system helped to reduce the overall incidence complications from 4.9% (225 patients) to 2.1% (102 patients). -
Diagnostic of the antioxidant system in children with chronic purulent rhinosinusitsSummary: In recent years the possibility of isolating groups of free radical pathologies. High sensivity of test reflecting the metabolic reaction of the membrane level in chronic sinusitis that’s explains the composition of cell membranes and obtain more information for assessing the severity of pathologic process. There were showing and treating 48children at age from 5 to 15 with an exacerbation of various forms chronic sinusitis. Applying of drug aktovegen shows not only therapeutics effect but proof his antioxidant effect which show how relapse are down after applying therapy it make possibility for recommendation necessary in complex therapy
Journal problems of biology and medicine -
The studies included reported data and medical history of children who received treatment in the chil-dren's department of the Samarkand regional TB clinic. The results indicate that morbidity in Taylak exceeds the regional indices by at least 2 times. Almost half of all patients were in the age 7-10 years. Contact with tu-berculosis patients is the most significant risk factors in the development of primary TB infection. High morbid-ity of children from the family contact. About half of affected children suffered from catarrhal diseases, which also can be attributed to the long and often ill children at risk for the development of active forms of primary tuberculosis. -
The results of toxicometric studies, which allowed to determine the toxicity parameters (LD 16 , LD 50 , LD 84 , LD 99 ) and hazard (absolute toxicity, acute toxic effect zone, tilt function, total and integral toxicity index) of germanium, magnesium and tartaric acid coordination compound (OKAGERM–4) for warm-blooded, in-cluding for humans. The data obtained make it possible to classify the compound as a group of low-toxic sub-stances (class IV) under conditions of intraperitoneal administration, which is the experimental basis for fur-ther, more in-depth studies of OKAGERM–4 as a therapeutic and prophylactic agent for correcting hypoxic syndrome -
Structural changes of the brain of babies at pneumonia according to ultrasonic researchThe authors based on the analysis and evaluation of the neurosonographic studies shows the effects of pneumonia on infant brain structures, which is amplified in a burdened background: perinatal nervous system lesions, jaundice, and congenital heart defect. The inflammatory response in pneumonia manifested by the appearance of numerous correlations that characterize the activity of voltage compensatory functions of organs and systems.
Doctor's Herald -
Disturbance of system erythron in clinic of the acute pneumonia at children of early ageAim: to study morphology of system crythron in clinic of acute pneumonia at children of early age. Materials and methods: the morphology of system crythron at 102 patients with the heavy pneumonia complicated hyperthermal, convulsive and toxic by syndromes aged from 1 till 3 flyings is studied. Boys - 38 (37,3%), girls - 64 (62,7%). Results: the analysis which is carried out by us at 102 patients with acute pneumonia against hyper thermal, convulsive and toxic syndromes has shown that at hyper thermal syndrome availability of oxyphilic normoblasts no more than 1%, availability of considerable destruction of normocytes, rcticulocytosis - 12,4 %o. At convulsive syndrome relative rcticulocytosis (21 %o), availability of oxyphilic normoblasts no more than 2%. At toxic dehydration the quantity of destructive normocytes fluctuated to 78%, and the quantity of reticulocytes was within 7 %o.
Doctor's Herald -
The aim of work was comparison of clinical performance of bronkhodilatator at children of early age. The analysis of clinical data at 48 patients has been carried out. The received results have shown that at patients of the I group (24) use of salbutamol promoted faster reduction of expressiveness of tachypnea, improvement of the general state, reduction of cyanosis of nasolabial triangle and cough, disappearance of symptoms of bronkhoobstruction. Whereas at the children of the II group receiving Euphyllinum (24), positive dynamics is noted in later terms and at small amount of patients. For 2-3 day of treatment of patients with Euphyllinum stopping of obstruction was noted only at 66,6% of patients, at salbutamol use full removal of bronkhoobstructive syndrome was noted at 91% of patients. Thus, good tolerance and fast improvement of clinical condition of patients proves advantage of purpose of salbutamol at treatment of bronkhoobstruction. -
Evolution of bronchitis in young patients from the point of view of instrumental and bacterial examination methodsWe examined 128 patients with the age from 18 to 35 years. 20 individuals without preexisting lower respiratory tract diseases were chosen for comparison as a seperate group. They were clinically and endoscop-ically dignosed with a foreign body of the respiratory tract and underwent bronchoscopy with bronchoalveolar lavage for bacteriological analysis. 108 patients were diagnosed with recurrent bronchitis (ICD-10 J.40). These patients were further divided into 3 groups. We also performed the additional bacteriologic analysis of feces in order to determine the relationship between changes in the bronchial microbiocenosis under the influ-ence of the antibiotic therapy in comparison with the changes in the intestinal biocenosis. 80% of patients from the group III (no lactobacilli bacteria and bifidobacteria), who received antibiotics, demonstrated chages in bronchial microbiocenosis, which were statistically different (р 0,05) from the parameters of the microbioce-nosis in the group I (control), where antibiotics were administered in 47,5%. In the patients from the group II, where antibiotic therapy was used in 72,2% of patients, either lacto- or bifidobacteria were found. However these changes were not significantly different (p0,06) from the parameters of the group I, which may indicate the incompleteness of negative changes in the bronchial microbiocenosis. Based on the acquired data we found lactobacilli bacteria and bifidobacteria in bronchoalveolar lavage in 100% of examined individuals, who had no prior lower respiratory tract diseases
Journal problems of biology and medicine -
The effectiveness of nebulizer inhalation with acetylcysteine in patients with bronchial obstructive syndrome was studied, the study of intestinal microbiocenosis was completed, and indications for the application of this method were developed. The results of the study showed the clinical and laboratory effectiveness of treatment of bronchial obstruction syndrome in children. -
Objective: to study genealogical aspects of acute obstructive bronchitis in children. Genealogical method was examined 210 children (probands) who were on inpatient treatment. The main group consisted of 160 children with acute obstructive bronchitis, and the control group consisted of 50 patients with acute bronchitis without bronchial obstructive syndrome. To calculate the index of burden, the Falconer model was used: in the main group, the index was 30%, and in the control group 1.2%. Segregation analysis by the method of M. Weinberg showed that the type of inheritance of acute obstructive bronchitis occurs in an autosomal dominant type. -
The efficacy of substitutive surfactant therapy for correction of oxidative stress manifestations in lung tissue after experimental thermal injury in dynamicComplex structural and metabolic changes in lung tissue after burn injury occur as a result of free radical processes activation under decrease of antioxidant protection enzymes activity and increase of endotoxemia. The correction of thermal trauma by surfactant reduces free radical processes and increases antioxidant enzymes activity in the blood and lung tissue of experimental animals and restores prooxidant-antioxidant balance that consequently causes the decrease of endogenous intoxication intensity
Journal problems of biology and medicine -
Chronic hypertrophic rhinitis lead to the breakdown of the normal functioning of the body because of a violation of respiratory function, leading to circulator}' and tissue hypoxia, biochemical disturbances, including lipid metabolism and activity of the antioxidant system, which is accompanied by the development of the inflammatory reaction of the nasal mucosa; breach of natural immunity, as well as organic lesions of the paranasal sinuses, pharynx, larynx, lower respiratory tract. The examination and treatment of patients with chronic hypertrophic rhinitis who after surgical treatment along with conventional treatment included medication elfunat (ethylmethylhydroxypyridine succinate). Use of the drug has contributed elftinat: reduction of postoperative inflammatory reaction region and improve the activity of reparative tissue of the nose, the normalization of blood lipid peroxidation system and morpho-functional restoration layer of nasal mucosa. -
Impact on lethal outcome measures to identify and dispensary observation tuberculosisWhen assessing and comparing the incidence of tuberculosis in different countries, it is necessary to take into account significant differences in the organization of identifying patients and establishing a diagnosis of tuberculosis. The true value of the indicator for incidence in any country of the world always differs from its recorded value. This difference, sometimes very significant, depends primarily on the efficiency of identifying TB patients, which varies not only in different countries, but even in individual regions within each of them.
Journal problems of biology and medicine -
Since the discovery of Mycobacterium tuberculosis (Koch's bacillus) - since 1882 - has died at least 200 million people from this disease . According to WHO annually in the world revealed by 8.9 million sick persons, 1.7 million died. The total number of cases is 50-60 million (this is equivalent to the population of France).
