The hepatoprotective activity of Ferula asafoetida resin gum in comparison with legalon was investigated in paracetamol hepatitis experimentally. It has been established that the gum of Ferula asafoetida resin prevents the development of cholestatistic and cytolytic syndromes, hyperbilirubinemia, hypoproteinemia. In terms of its pharmacological activity, the gum of Ferula asafoetida resin is not inferior to legalon. Obtained results recommend further studies of the pharmacological properties of the gum resin of Ferula asafoetida and the development of its officinal drug form
Мақолада брикет тайёрлашда кўмир таркибининг ахамияти тахлил қилинган.
This study focuses on the mechanisms of financial support for land use in the country and the creation of a legal framework for protecting the legitimate interests of landowners, regulating contractual relations, and gratuitously disposing of crops.
To assess the safety of the new carbon hemosorbent, the authors carried out experimental studies on 138 white laboratory rats of the nature "Wistar" and 16 mongrel dogs with toxicological, biochemical and physiological studies. The simulation of the mechanical block was carried out according to the author's methodology. The authors studied the acute and chronic toxicity of carbon hemosorbent with intragastric, intraperitoneal administration of the drug, and also evaluated the local irritant, skin-resorptive effect. The research carried out by the authors showed that carbon hemosorbent can be recommended in the complex treatment of liver failure.
There are several programs of geographic information systems, which are enriched with new improved versions from year to year. Even with the connection to the internet through these programs, the possibilities of carrying out many cartographic works are increasing. For example, it is important to create interactive dynamic maps on different topics. At present, the process of obtaining an intensive - interactive map for moving and changing objects in the spheres of population and population service is character. Maps of the population are necessary for ensuring and satisfying the practice of the national economy, culture and social development. According to the content of the maps of the population, the settlement of the population and its location are divided into maps, demographic, ethnographic anthropological and socioeconomic maps. In this article, opinions on the role of modem GIS technologies in the formation of attributive data and obtaining results and geolocation work on the database are given in the compilation of demographic maps based on the data of the last years.
The preventive wound infection remains by an actual problem of modem surgery, that is connected to high frequency aftcropcration wound of complications, which reaches up to 48.7 % in emergency surgery.
Per the last years the increasing application find electrolysis of water solutions sodium hypochlorite, which arc successfully used of purulent surgery, for want of treatment peritonitis, cavities formations of a liver and other.
However, this antiseptics about today was not applied in prophylaxys wound infection.
The author for the first time uses electrolysis of water solutions sodium hypochlorite in preventive wound infection and offers a method aftcropcration of processing of hands of the surgeon in a regime 0.4%-5 minutes, methods intraopcration the express train -processing of surgical gloves in regimes 0.4%-3 minutes and 0.6%-2 minutes, methods intraopcration the express train - processing of surgical tools in regimes 0.3 % during 7 minutes, 0.4 % during 5 minutes, 0.6 % during 3 minutes and processing in a regime 0.05 % during 45 minutes.
For estimation of clinical efficiency of the developed complex intraopcration of preventive wound infection the author develops clinical mark scales on distribution of operations to groups of risk of development wound infection, mark scale of estimation of a condition postopcration wound and scale of estimation of outcomes of healing of wounds.
The clinical material includes an inspection and treatment 643 patients. From them control group included 453 patients and in the basis group included 190 patients. The developed complex intraopcrctation of preventive wound infection has shown high efficiency. Use of the developed complex of preventive wound infection has allowed to reduce frequency wound of complications from 15.3 % up to 8.9%.
Any epidemic and pandemic that is a great stress or emergency leads to disruptions in the psycho-neurological system and human behavior. Psycho-emotional excitement in patients with severe Covid-19 dramatically reduces the effectiveness of non-invasive ventilation. Purpose of the study: to assess the efficacy, safety and impact on the quality of life of patients with dexmedetomidine and propofol against the background of a decrease in need for oxygen. The study included 21 patients with severe and extremely severe Covid-19. In the first group of patients with fear of death, a combination of drugs propofol + sibazone + fentanyl was used. In the second group, dexmedetomidine and promedol. Conclusions: in patients with a severe course of coronavirus infection, dexmedetomidine is more effective in reducing psycho neurological arousal and improving cognitive functions, which leads to an effective supply of oxygen and to their faster recovery.
Subjects of research: 815 patients with the various forms acute pancreatitis, 235 patients with primary erronous diagnosis of acute pancreatitis.
The purpose of research: improve the treatment results of the patients with acute pancreatitis by upgrading existing and developing new diagnostic methods in the treatment complex.
Methods of research: clinical, biochemical investigation.
The results achieved and their novelty. On the basis of the analysis of occurance frequency of various clinical symptoms, diagnostics system of the acute pancreatitis is offered, the criteria of the laboratory and ultrasonic diagnostics for given disease arc advanced, for a quantitative estimation of severity of a condition of the patients the ball scale is offered; the complex conservative therapy is advanced, the technique of realization of long intraarterial catheter therapy is optimized, the optimum indications to realization of retrograd and pcrcutanc endobiliar interventions in treatment of acute biliar pancreatitis arc determined, drainage and sanation of omental bag for open operative interventons is offered, the technique of treatment of the patients in postoperative period is advanced and the algorithm of medical measures is offered at acute pancreatitis.
The developed diagnostic and treatment complex has allowed to reduce frequency of diagnostic errors from 28,4% to 16,8%, to increase efficiency of conservative therapy from 89,8% up to 95,3%, long intraarterial catheter therapy -from 72,0% up to 82,8%, to reduce mortality from 7,4% to 3,4%.
The practical importance. The offered clinical system for diagnostics and the advanced criteria of laboratory diagnostics promote to increase reliability of diagnostics, the systematized ultrasonic criteria allows verify the form of acute pancreatitis. The offered scale of definition of severity of the acute pancreatitis allows quantitatively characterize a condition of the patients, dynamical changes of pathological process and efficiency of used of a complex of medical measures. The advanced complex conservative therapy, technique of realization long intraarterial catheter therapy, definition of the indications to performance retrograd and pcrcutanc endobiliar interventions, advanced draining method and sanation of omentum bag at pancrcanccrosis, combined treatment in postoperative period allow to improve results of treatment of the given category of the patients.
Degree of introduction and economic efficiency: the received results arc introduced into practical activity of surgical branches of second clinics TMA.
Area of application: emergency and abdominal surgery.
In children’s tuberculosis inpatient departments of the PMCforPhandP and the Tashkent city tuberculosis hospital, 272 children and adolescents with various forms of tuberculosis were examined. Among children with various forms of tuberculosis, 28(10,3%) patients were diagnosed with complicated forms and 244 (89,7%)-uncomplicated forms of tuberculosis. When studying the risk factors for the disease, it was revealed that there were 225 (87,7%) children vaccinated with BCG, of which 58 (25,8%) children (76,8%), of whom anemia was found in 35 (12,9%) patients. In the structure of clinical forms in childrenand adolescents with tuberculosis, tuberculosis of the intrathoracic lymph nodes (57,0%) and primary tuberculosis complex (11,0%) predominate. Most of the children hada positivity to tuberculin (77,5±2,5%) and to the test for Diaskintest (69,5±2,7%).