All articles - Obstetrics and Gynecology
Number of articles: 743
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Peculiarities of clinical flow in premature extraction of near fetal water and the principles of maintaining pregnant womenPremature rupture of the membranes (PROM) is a complication of pregnancy, characterized by a violation of the integrity of the membranes of the membranes of the membranes and the outflow of amniotic fluid (before the onset of labor) early pregnancy, accounting for 34 to 56% of all preterm births [7, 12]
Journal problems of biology and medicine -
Pathogenetic aspects of disorders of carbohydrate and fat metabolism in menopausal womenThe World Health Organization estimates that more than a billion people on the planet are overweight or obese. At the same time, in the countries of Western Europe from 20–25% women are obese. A feature of obesity is that it is often combined with serious diseases that lead to a reduction in the life expectancy of patients: with type 2 diabetes mellitus, arterial hypertension, dyslipidemia, atherosclerosis, coronary heart disease, sleep apnea syndrome, some types of malignant neo-formations, reproductive disorders, diseases of the musculoskeletal system. But the most important aspect of the problem of obesity is its relationship with type 2 diabetes mellitus. The risk of developing type 2 diabetes mellitus (T2DM) is significantly increased is directly proportional to the body mass index and the severity of dyslipidemia. Currently, the number of patients with diabetes is 177 million people, and 90% of patients are patients with type 2 diabetes. Almost over the past 20 years, the number of patients with diabetes in the world has increased by 6 times. By 2020In 2009, the number of patients is projected to increase to 300 million people. It should be noted that women over 45 suffer from DM twice as often as men [1, 2].
Journal problems of biology and medicine -
Comparative clinical study of post-placental and interval iud administration in women who underwent cesarean sectionResearch Objective: to compare the rates of postplacental use of IUD С T380A in women who underwent cesarean section with clinical outcomes of IUD used at intervals. 6 weeks after abdominal delivery. Research methods: The study was carried out in Maternity Hospital No. 2 of the Samarkand city to assess the clinical outcome of postplacental and interval insertion of Си T 380 A in women who had undergone cesarean section. Study results: This study was a prospective clinical follow-up of women who had undergone cesarean section and agreed to participate in our study. First of all, we observed the expulsion of the IUD. The expulsion results after 6 months of observation in both groups were the same. The satisfaction with the method also did not differ significantly from the interval IUD insertion. Conclusions. Post-placental administration of Си T 380 A IUD during caesarean section is a practical, convenient, safe, effective and acceptable method of contraception.
Doctor's Herald -
Along with surgical diseases, patients with an increasingly common cardiovascular disease (20%). arterial hypertension (60%), vascular dystonia (70%), cerebral circulatory disorders, or a history of stroke are more common. The importance of preoperative preparation of patients has increased, in particular, the demand for therapeutic premedication has increased [1-3]. In operative gynecology, a similar situation occurs in women aged 40-55 years with menopausal uterine fibroids. The aim of the study was to determine the effectiveness of the use of climadynon and grandaxine as part of therapeutic premedication. -
In the structure of gynecological diseases, the incidence of genital warts is 28%. and 15% of surgeries arc performed on this pathology. Genital prolapse among women: 10.1% under 30 years, 40.2% at 30-45 years, over 50 - 50 Such disorders lead to problems with urinary incontinence, constipation, decreased libido and sexual dysfunction. -
The review is devoted to one of the most relevant sections of modem obstetrics - nausea and vomiting of pregnant women. This review article summarizes recent data on the antenatal diagnosis of nausea and vomiting, provides a modem classification of the severity of the pathology, and describes the complications of excessive vomiting in pregnant women. The article analyzes various treatment options for nausea and vomiting, including those based on updated AGOG recommendations. -
Complex approach to the treatment of patients with dystrophic diseases Of vulva in different age groupsThe premalignant diseases of the skin and mucosa of external genitalia are dystrophic diseases of the vulva against which in 20-60% of cases there is cancer. The material of this study selected a retrospective analysis of 50 patients treated for dystrophic diseases of the vulva. As a result of the treatment of dystrophic diseases of the vulva in women of reproductive age, drug treatment with hormone therapy (local and general use) and cryodestruction, is a more effective and minimally invasive method. In menopausal age and climacter-ic age in women due to of the in effectiveness of drug treatment without hormone therapy in most cases leads to the application of surgical intervention
Journal problems of biology and medicine -
Assessment of the perinatal risk of premature birth in women with Pulmonary tuberculosisThe analysis of factors of perinatal risk of premature birth in women with pulmonary tuberculosis is conducted. A high perinatal risk of obstetrical complications on the background of the tuberculosis process is established. It is shown that under tuberculosis the premature birth is a cause of perinatal pathology, morbidi-ty, disability, and child mortality. It is proved that perinatal pathology and mortality are associated or deter- mined by premature birth and leads to an increase in the level of insufficient weight to the term of gestation of children, and the mortality in this category of newborns is 33 times higher in comparison with full-term chil-dren
Journal problems of biology and medicine -
Obstetric and gynecological anamnesis features of mothers with hemolytic disease newbornThe analysis of pregnant women's cards and the birth history of 50 women who gave birth to newborns with hemolytic disease was carried out. It is revealed that the most significant risk factors for the development of hemolytic disease of the newborn are: abortion, threatened miscarriage, anemia of pregnant women. A high correlative relationship was noted between the occurrence of GB due to Rhesus conflict with maternal parity, abortions, anemia of pregnant women, in newborns born to ABO of a conflict pregnancy with the first pregnancy of the mother.
Doctor's Herald -
The role of the nurse for the prevention of uterine cervical diseasesCorrect and competent organization of the nurse's work of the examination room, contributes to the in- crease of detectability of cervical disease and can be one of the most promising and effective forms of preven-tive examination of the female population
Journal problems of biology and medicine -
Профилактика венозных тромбоэмболических осложнений у беременных с варикозным расширением вен малого тазаThe use of 600 mg phlebodia in pregnant women with varicose veins of the pelvis is pathogenically grounded and effective. The reduction of the main clinical manifestations of this pathology in combination with the stabilization of the disturbed parameters of the blood coagulation system made it possible to prevent such formidable complications of pregnancy as venous thromboembolic complications in pregnant women at high risk
Journal problems of biology and medicine -
Comparative analysis of characteristic indicators of patients with ovarian cancerThe article discusses the comparative analysis of characteristic parameters of patients with ovarian can-cer. We made a questionnaire for them to study the lives of these patients. The questionnaire contains 17 ques-tions that determine the anamnesis of patients. And willing patients were allowed to respond anonymously
Journal problems of biology and medicine -
Analysis of neglected cases of cervical cancer in the samarkand regionIn this paper, the analysis of advanced cases of cervical cancer in recent years. The degree of dissemina-tion of tumor process at the time of diagnosis is the major prognostic factor that determines the course of the disease and fate of cancer patients. This trend is alarming, as the quality of services depends on the timely per-formance of diagnostic procedures and further treatment strategy and prognosis of malignant neoplasms
Journal problems of biology and medicine -
Peculiarities of the response of the respiratory disorder syndrome in deeply- DiseasedTwenty deeply depressed with respiratory distress syndrome were examined. It was revealed that this syndrome in deeply premature in the early neonatal period is characterized by a change in the surfactant system, the clinical picture of which is characterized by a prolonged development of respiratory failure symptoms, disseminated small atalec-tasis. and air bronchogram symptoms from the first days of life.
Doctor's Herald -
The mammary gland cancer is one of the most serious problems of modern oncology at the expense of prevalence and the psychological aspects connected with it. For women of able-bodied age the mammary gland cancer is one of principal causesinvalisisation and death rates -
In recent years, in the Department of gynecology, often performed extirpation of the uterus. This is due to the fact that drug therapy does not give the desired effect. Only according to the first clinic of Sammi only in 2017, constituent part of extirpation of the all 136 laparotomic operations, uterine fibroids accounts about for 46.3%. Purpose: was to study the effectiveness and safety of the method of anesthesia. Method: was to carry out various types of anesthetic support for identical operations and determine the most effective method of anesthesia. As a result: all methods ofanesthesiological support had an effective level of anesthesia. There was no special differentiation between different methods.Conclusion: The best parameter was the method of combined spinal-epidural anesthesia, which provides a good during of the anesthesia and protects the body of patients from surgical aggression. In addition, this method has a more stable hemodynamics, relative to the other two groups (total intravenous anesthesia and spinal anesthesia), which favorably affects the course of the operation. -
The use of l-karnitin in newborn infants with perinatal hypoxic lesions of the central nervous systemIn the light of scientific research, a deficiency of carnitine is observed in newborn children, which leads to disruption of the process of fatty acid transfer into the mitochondria. In groups of children from 60 newborns with various pathologies of the central nervous system (CNS), carnitine was included in the treatment; on the basis of clinical laboratory and instrumental methods of research, positive dynamics was established at a faster time with the restoration of normal activity of mitochondria succinate dehydrogenase (SDH) and alpha glycer- ophosphate dehydrogenase (αGDPH).
Journal problems of biology and medicine -
Clinical and epidemiological characteristics of women patients with gonorrhoea in samarkand regionThe data of 3 years period of clinical epidemiological studies of 120 female patients with gonorrhea living in Samarkand Region have been presented in the article. The features of epidemiology, clinical pictures of 38 patients with recent acute gonorrhea. 20 patients with torpid. 19 patients with sub acute and 25 patients with chronic gonorrhea have been shown at the contemporary level. The highest morbidity for gonorrhea is observed among the persons dealing with paid sexual service (29.41%) and unemployed women (53.92%). Gonorrhea is more often observed in 18-30 years ago group, that makes 79.41%. In descending recent acute gonorrhea urethra is involved into the process in more than 3d of women, i.c. in 76.47% of cases, cervical canal-100%, vulva-5.88% and vagina -2.94%. Ascending gonorrhea was observed in 13.16% of patients. In torpid, sub acute and chronic forms of the disease descending gonorrhea occurred in 59.37% of cases, ascending in 40.63%.
Doctor's Herald -
A new, highly effective complex method of treatment of patients with torpid, subacute gonorrhea in women has been developed in the presented in the presented article. It includes administration of i'm ccfriaxon, 1g, 2 times daily for 3 days with simultaneous combination of oral azitromycin, 0.25 g 2 times daily with the course dosage of 3 g and intravaginal suppositories, consisting of 2.0 g of cacao oil. 25mg of chimopsin, 0.02 g of gentamycin. As a result of therapy rapid control of inflammatory processes, 100% of recovery and sufficient decrease of postgonorrheal residual inflammatory phenomena (7.7% against 53.8% in the group of comparison)took place. -
Cesarean section is one of the most common surgical interventions in the world, and its frequency continues to increase, especially in high and middle income countries. Although a cesarean section can save lives, it is often performed in the absence of medical indications, which puts women and their children at risk of developing health problems in the short or long term. -
Immunological aspects of vitamin «d» deficiency in pregnancyIn this article the effect of a reduction and the lack of vitamin “D” to the pregnant woman's immune sys-tem have been leant learnt. Owing to the reduction of vitamin “D”, obvious changes will occur in the immune system of a pregnant woman During pregnancy. This condition can be seen when T- suppressor immunity de-creased. In other words, it makes natural killer cells active. As a result, they go though placentar barrier and it effects aggressively to the fetus. It leads to the deterioration of blood circulation, and it brings out improvement in patalogic conditions during pregnancy
Journal problems of biology and medicine -
Ray visualization of breast pathology in women depending on thyroid statusAnalyzed the results of X-ray sonography of 200 women with mammary gland pathologies. In women with mammary gland pathologies, thyroid hypothyroidism was noted in a somewhat prevalent percentage of observations, confirmed by radiometry and laboratory data. When ypothyroidism is determined by an in-crease in the number of observations of fibroaden and diffuse fibrotic mastopathies, characterized by pro-nounced fibrosis processes and a violation of regression of the glandular tissue. The reverse situation is ob-served in the occurrence of mammary gland cysts and normal tissue structure, the number of such observations in patients with hypothyroidism was significantly less than in patients without hypothyroidism. In women with hypothyroidism and without hypothyroidism, almost the same number of cases of breast cancer
Journal problems of biology and medicine -
Inflammatory changes in the mother – placenta –fetus system at antenatal fetal deathInflammatory changes in the placental system is a widespread obstetric -gynecological pathology, which is one of the main causes of spontaneous abortions and fetal death. Vaginal dysbiosis, increased and massive seeding of pathogenic microorganisms, infection of the placenta - create an unfavorable background for the course of pregnancy, infect the placenta, amniotic fluid and thus lead to microbial contamination of the fetus, with its subsequent death.
Doctor's Herald -
Objective: to determine the possible role of endotoxin aggression in the pathogenesis of preterm labor. Materials and methods: we examined 48 pregnant women with a history of complications (abortion, premature birth), as well as 20 pregnant women with a physiological course. Studies on dysbiosis of the vagina and intestines, determination of the concentration of lipopolysaccharides (LPS), the concentration of neopterin concentration, the concentration of diamine oxidase were studied, the cytokine status, the study of histamine, the assessment of the necrotic tumor factor FNO - a were studied. Result: analysis of studies determined the effect of the degree of intestinal and vaginal dysbiosis on the level of lipopolysaccharides (LPS). Pregnant women with the risk of premature birth have an increase in serum TNF-a 2 times. IL-ip 3 times and IL-8 5.4 times in comparison with the physiological pregnancy, the average level of LPS was significantly higher than in pregnant women with physiological pregnancy. Conclusion: the study showed that bacterial endogenous intoxication from the intestine and vaginal secretion is accompanied by severe endotoxemia and a decrease in the specific immune response in pregnant women at risk of developing preterm birth compared with the physiological course of pregnancy. -
Preeclampsia (PE) is a disease that continues to be the main cause of maternal and fetal mortality and complications in 5-8% of pregnancies, reaching 11% at premature birth, develops after 20 weeks of pregnancy and is characterized by hypertension and proteinuria. According to WHO. hypertension during pregnancy is the cause of 9 to 25 per cent of all maternal mortality, but accurate data arc difficult to determine. In addition to the fact that PH is one of the leading causes of maternal and perinatal mortality, this disease and its complications cause a range of medical problems.
