No. 4,1 (85) (2015) Problems of biology and medicine

Статьи

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  Estimate relations polymorphism gene FcεRIβ with allergic asthma Important candidate for the major gene predisposition to asthma is completely gene FcεRIβ. The distribution of alleles and genotypes 109T/C polymorphism in allergic asthma FcεRIβ. The results show that markers of increased risk of allergic asthma are genotype FcεRIβ-109T/T allele and FcεRIβ-109T.

  Sh Ziyadullaev

  53-54

  79   13

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  Acute respiratory agents of viral infection in the extragenital structure diseases in reproductive age woman The problem of acute respiratory viral infections (ARVI) still remains relevant at the present time. At the beginning of this century, the emergence of new infections with a high mortality rate caused by avian influenza viruses (A / H5N1, A / H7N9) and coronavirus themselves (severe acute respiratory syndrome - SARS, Middle East respiratory syndrome - MERS-CoV). A new influenza A/H1N1pdm09 virus has caused another pandemic. The A/H5N1 and A/H7N9 avian influenza viruses also have pandemic potential, which could be realized if sustained human-to-human transmission occurs.

  G Yusupova, N Zakirova

  196-197

  93   14

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  Principles treatment of chronic eczema in workers in agriculture The given article describes the significant decrease of SD 3 - lymphocytes (T-cells), CD-4 lymphocytes (T- helper cells), the absorptive function of neutrophils and average importance of IgM in patients with chronic eczema. The Factors of SD-22 (B-cells) and CIC (circulating immune complexes) as well as the average importances of IgA and IgG of all patients were higher than reliable factors. Using Immunomaks in complex with traditional terapy prevents the development relapse disease (12.5% against 75,0 % in group of the comparison (R<0.01) and greatly shortens the peri-od of the treatment

  R Narzikulov

  87-89

  56   21

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  Therapy of allergodermatosis рolioksidoniy in combination with еrius and reosorbilakt In this article the author developed a new highly effective complex method of treatment of patients with an aller- gic dermatosis, including prescription a polioksidoniy intramuscular on 6 mg, within 6 days, in a simultaneous combi-nation to an antigistaminic armacy erius orally and reosorbilakt intravenous drops within 7 days. Author carried out (before treatment) the analysis of a clinical current and dynamics of laboratory indicators which is noted reliable in- crease of indicators of the maintenance of Ig E in serum of blood of patients of an allergodermatosis. As a result of the carried-out therapy fast knocking over of skin process and sharp shift of level of the maintenance of IgE towards nor- malization is shown.

  R Narzikulov

  84-86

  90   18

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  Effectiveness of screening in the diagnosis of cervical disease With the right collection of material for cytological examination in compliance with all requirements of the capture and fixation of smears, in the presence of well-equipped laboratories and trained cytology cytology screening to detect precancerous changes using the Pap test has a high sensitivity and can be widely used in medical practice.

  D Nazarova, N Sulaymanova, N Parvizi

  82-83

  102   23

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  Clinical characteristics of patients women of cervical diseases It was carried out a comprehensive survey of 50 women with cervical ectopia, which showed the presence of background diseases, contributing for cervical disease, which must be considered when treating such patients.

  D Nazarova, N Sulaymanova, Z Mahmudova

  80-81

  71   19

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  On the question of the relevance of early diagnosis of uterine fibroids Clinically examined 91 patients with uterine myoma. The dependence between the time of occurrence of the main clinical complaints of patients with MM, in particular, menstrual dysfunction and prescription primary diagnosis of the disease. Defined time period extending from the moment diagnosis of this disease before surgery. It was revealed that the surgery is performed in the presence of already expressed extragenital and genital complications of MM.

  Z Mahmudova, N Parvizi, N Karimova

  77-79

  104   21

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  Features of the stroke etiopathogenesis in individuals at the gerontological age About 80% of strokes occur in people over 65 years, and the age has a great influence on the outcome of disease. Increasing the probability of the incidence of stroke in the elderly are conditioned by age – related changes in the brain. The risk factors of the acute disorders and mechanisms of the ischemic brain lesions are different at the older and younger age. Stroke in the old patients is more severe. However, the old patients often receive less effective treatment than the young, which leads to adverse outcomes

  J Mardono, D Burieva, D Ahmedova, S Khakimova, A Jurabekova

  74-76

  185   19

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  Clinic and diagnosis of tumors of hypopharynx Improving early diagnosis of tumors of hypopharynx and organization of specialized care to patients - a common goal of oncologists and otolaryngologists, the achievement of which will effectively treat these patients. In a large clinical material analyzed the data of the clinical course and given a detailed assessment of each of the methods of diagnosing tumors hypopharynx. It was concluded that the feasibility of using fibroendoskopicheskogo research to identify a benign tumor in the early stages of the hypopharynx.

  G Lutfullaev, Sh Kobilova, Z Mirzaev

  71-73

  74   14

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  The role of general practitioner in the organization of geriatric service in the primary health care system The aim of the performed investigation was the study of physical status, data of morbidity and elaborates approaches to improve health status of elderly people in the rural places of Uzbekistan. 172 people at the age more than 65 years old have been examined with the use of screening method: 92,3% of elderly people live with thieir families, 7% of them live with relatives and only 7% live alone; among elderly people 67 were women (38,9%) and 105 were men (61,1%). There have been 14 people (8,1%) at the age more than 80 years old. During the assessing of functional status with the use of Bartel’s scale in 89% of cases it has been examined 80 and more points, i.e. they could service themselves. In general in 47,8% of cases different types of diseases, such as arterial hypertension, ischemic heart disease, osteokhondrosis and osteoarthrosis have been observed.

  S Lapasov, F Abdurasulov, B Yuldashev, L Khakimova, M Valieva

  67-70

  116   15

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  Clinical and neuroimaging comparisons in acute ischemic stroke The article presents the results of the analysis of clinical - neuroimaging comparison in 48 patients with acute is-chemic stroke. In assessing of neurological status international scales (European Stroke Scale, Fugl-Meyer Scale, Motor Assessment Scale) and the results of MRI – research have been used.

  Kh Kulmirzaeva, D Burieva, Z Mavlyanova, O Kim

  64-66

  126   20

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  Electroencephalography epilepsy in different age groups Study elektroenctphalographical parameter in epilepsyin different age groups. Examination of 168 patient with epilepsy, is included a group of children early young age a group of adults and adolesance age. The analysis EEG in children is shown in 76% of bioelectrical activity of the cerebrum does not correspond to the age rate. In the elderly age have place partial epileptic stroke for confurmation of epilepsy age playsan important trole

  N Kudratova, L Khamrayeva, N Abdullayeva, A Jurabekova

  59-63

  229   22

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  Hygienic evaluation of academic load and quality of the organization of educational process in the various educational institutions The estimation of the organization of the educational process, including the amount of the basic academic load and extra curricular activities of children enrolled in secondary schools, academic lyceums and vocational college of Tashkent. Hygienic assessment schedules showed that the timetable drawn up without taking into account the dynamics of the load matching daily and weekly health of children. Assessment of the quality of the educational process indicates that the highest proportion of difficult items marked in the lyceum and school. The total workload of students training sessions (classes in school, preparing homework, tutoring) is very high: college students spend an average of 8-9 hours, and lyceum students and high school - 11-13 hours a day.

  R Kamilova, B Abdusamatova, L Isakova, Z Mavlyanova

  55-58

  307   35

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  The echinicoccosis seroepidemiological investigation The larvocystes are localize in the liver (59,75%) and lungs (16,86%) and the 0.24-2.4% – in the another organs. The total seropositivity of the population in Namangan region was 6.2%; the quantity of the investigated persons on the whole with diagnostic titer – 9.7%.Taenidosis ova’s in the 1 kg soil was from 50 to 100; the quantity of ascaris ova’s – 50 and trichocephalus ova’s – 50-100.

  T Abdiev, D Saidakhmedova, U Suvonkulov, L Kachugina, T Vahobov, Z Abidov, H Arziev

  8-9

  125   16

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  Risk factors for development of chronic endometritis in women with reproductive disorders Inflammatory diseases of the reproductive system continue to take one of the first places among the causes of repro- ductive disorders. A high frequency of chronic endometritis in women with reproductive disorders is registered and in modern conditions, it has no tendency to the decrease. The research is dedicated to the analysis of the data of the anamnesis of 60 women with chronic endometritis and reproductive disorders. Patients who visited doctor in con- nection with reproductive disorders underwent complex examination. It included the data of the anamnesis, general clinical and gynecological examinations, laboratory and instrumental methods. Verification of diagnosis of chronic endometritis was carried out following the results of the histological examination of the endometrium. In the group of women with chronic endometritis 56 % (34) of women complained of miscarriage, in 20 % (12) there was diagnosed primary infertility, and in 24 % (14) – secondary infertility. It was revealed that in patients with chronic endometritis diseases of gastro-intestinal tract, kidneys, and upper respiratory tract dominated among somatic pathology. A high percentage of women had urogenital infections in the past. Those infections were determined in 49 % (29) of women, 65 % (39) of those patients had mono-infection. Chlamydia, trichomoniasis, and viral infections prevailed among patho- gens. Women with chronic endometritis more often had operative interventions on the abdominal organs. Percentage of women 56 % (34) with indication for curettage of the uterus regarding terminated pregnancy (after spontaneous abortion or non-developing pregnancy) is high, 25 % (15) of them had both miscarriage and non-developed pregnancy in history and 20 % (12) of patients had from 2 to 4 curettage of the uterine cavity. The percentage of complicated deliveries and abortions was 28 % (17).

  N Zakirova, Y Tangirova, M Fozilova, G Indiaminova

  50-52

  166   25

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  The effectiveness off topiramat in the treatment of epilepsy in children with infantile cerebral paralysis The results of effectiveness of medicine Topiramat in the treatment of epilepsy in children with cerebral spastic infantile paralysis are given. In examination 37 children were involved; epilepsy was diagnosed on the basis of classification , clinic neurological examination and data about EEG. Special biochemical methods of research included definition of miсroelementes (Na, K, Ca). The medicine was prescribed for 6 month. In all, patients taken Topiramat the sodium level fell, an increase in Na, K, ATP, Ca , ATP, the dynamics of EEG and decrease in attacks significantly changed.

  I Zhuraeva, M Abdusalomova, A Jurabekova

  45-49

  150   21

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  Comparative characteristics of the methods of treatment of patients with posttraumatic defects and deformations of the bottom wall of orbit Increasing the number of patients with injuries of the lower wall of orbit helps highlighting the development of new and improvement of existing treatments. That, in turn, leads to the need for thorough research posttraumatic de-formation of the bottom wall of the orbit in the diagnostic aspects, as well as for improving methods of medical reha-bilitation

  A Zhilonov, D Tuychibaeva, A Khakimov, Sh Yusupov

  42-44

  86   17

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  Myogenic pain in children and adolescents: the clinical and neurological features This article presents the results of a study of clinical and neurological features of myogenic pain in children and adolescents. We have examined 60 organized children, which were divided into 4 groups according to the educational institution. All patients were carried out neurological checkup, the study of muscle tone, visual analogue Scale (VAS) to assess the quality of life used a special questionnaire SF-36

  J Dusanov, Z Mavlyanova, A Jurabekova

  38-41

  143   19

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  Innovative aspects of the treatment of craniofacial co-abdominal injury Combined Craniofacial-abdominal injury (CCFAI) is one of the most difficult types of injuries and has great so-cial importance, both because of its prevalence, and a large percentage of poor outcomes. We examined 63 patients with CCFAI admitted on an emergency basis after the injury. Depending on the severity of the general condition of the pa-tients were divided into two groups. According to survey thus, 52% of patients with CCFAI were conscious, in 48% of patients have noted a violation of consciousness in the form of sopor, coma, and stunning. Of the 48% of patients in an unconscious state, 23% were performed diagnostic laparoscopy. At the same time 15% of the observed damage of parenchymal organs (rupture of the liver, spleen, kidneys). The optimal method of screening patients with CCFAI is ultrasound and MRI of the abdomen

  Sh Boymuradov, R Yangiev, D Ibragimov

  35-37

  113   19

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  The impact of the temperament on the choice of the type of sports activity This article present a summary of the concept of the temperament, its types, basic properties and the impact on the choice of the type of sports activity, depending on the individual characteristics of the sportsman. It describes the dominant factors in the definition of typological feature.

  S Baratova, Z Mavlyanova, O Kim

  32-34

  182   24

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  Post- stroke depression in the recovery period Undoubtedly correction of depressive disorders is essential in the outcomes of stroke in patients with depression. We should notice that patient with stroke is usually the elderly person burdened with various somatic diseases, with a reduced rate of metabolism of drugs and receives at least three types of medication a day. The lesions of different localization in the depressions with various psychopathological pictures are distributed alm ost evenly. Implementation of Stimuloton combined with non-drug measures is effective in the vast number of stroke patients for controlling the depressive disorders, for improving psychosocial adaptation, and thus for enhance the quality of life.

  D Ahmedova, D Buriev, J Mardonov, S Khakimova, A Jurabekova

  28-31

  265   23

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  Efficiency of application of povidon-iodine at processing of a residual cavity after echinococcectomy of a liver Results of surgical treatment of patients with echinococcosis of a liver are analyzed by various ways of antiparasitic processing of a residual cavity. The obtained data of researches have allowed to conclude, that Povidon-iodine application in processing of residual cavities after echinococcectomy from a liver reveals its expressed pernicious action on all types of germinal elements of echinococc and its rather harmless influence on a macroorganism at intraoperative application provides possibility of wide use of this preparation in surgery practice echinococcosisof various localization, with the purpose of preventive maintenance of postoperative complications and disease relapses

  R Ahmedov, B Khamdamov, Kh Inoyatov, F Tagaev, I Khamdamov, A Khamdamov

  24-27

  131   34

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  Clinical aspects of modern methods of induction of premature birth The goal: a comparative analysis of methods of induction of preterm labor, performed by various methods, and evaluation of its safety. Materials and Methods: 60 women were examined: 30 women labor induction of mifepristone and misoprostol, 30 women Glandin E2.Rezultaty induction of labor: during the methods of induction with misoprostol in combination with mifepristone shortened the average length of time kind of decreases the need to use additional interventions. Conclusion: The method of induction of preterm labor with misoprostol mifepristona- efficiently and more safely

  F Atakhodjaeva, H Alimova

  22-23

  136   23

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  Student activities at leisure from training sessions A survey of 514 students from 7 to 18 years, enrolled in various types of educational institutions of Tashkent. It was determined that only 3.2% of children do not watch TV every day, whereas the activities in front of TV at 25% of pupils of 1-2 hours, while 7.1% - 3 or more hours a day. 67.5% of households had computers at home, and the children spend time mainly on games and entertainment. On average, 47% of children have mobile phones: Time to talk on a cell phone for 30 minutes to 2 hours per day students-athletes is 2.5 times lower than their peers who are not involved in sports. Only 3% of children do not have a home help; students not involved in sports, 1.8 times more time spent at work in the household. Walking in the open air on a daily basis make 61.5% of the students, of which only 14% - up to 3 hours per day. Children with athletes because of their training and sports, spend less time outdoors. Sleep duration of less than 6-7 hours, to a greater extent, has characterized children, that are not athletes.

  B Abdusamatova, L Basharova, J Komilov, Z Mavlyanova

  18-21

  118   16

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  Clinic aspects of chronic posttraumatic headache in children and adolescents In examination hundred patients children with chronic posttraumatic headache are involved. Clinic neurological examinations, electroencephalography analysis, neuropsychological examination with the help of scales (of Spilberg-Khanin, methodic by Luria) were carried out for children. The results show data about unfavorable factors strengthening the process of psychogeny and leading to chronic disease

  M Abdusalomova, I Zhuraeva, D Abdullayeva, A Jurabekova

  15-17

  143   20

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