No. 2 (94) (2017): Problems of biology and medicine

Presented results of surgical treatment of old dislocations of caput of radii. Findings of searching were based on results of surgical treatment 37 patients with dislocations of caput radii on different reasons. Patients were done open reduction of caput of radii with repair of ligament annular. For modernization methods of re-pair of ligament annular we used its capsule of the joint and pats of ligament annular which has more anato-my-physiologically for elbow joint. By this method we have good and satisfactory functional results on 97,4% cases and anatomical on 95,7% cases

The paper describes the relationship of psychogenic stress with the manifestation/exacerbation of pem-phigus. Reviewed psychosomatic mechanisms of manifestation of pemphigus. The authors identified the rela-tionship of clinical manifestations of pemphigus to psychogenic disorders

Create a canopy above the head of the femur is distribute method of surgical treatment aimed at the res-toration of supporting ability and the dysplastic hip joint pathology. This article describes a method developed by the authors of surgery 11 older children and adolescents with congenital hip dislocation. This option of sur-gery is an effective treatment for children aged 7 to 18 years in violation of the relations hip dysplastic genesis

The peculiarities of the personality type of GB patients (according to Young's criteria) and the degree of
depressive disorders in patients with 42 hypertensive patients (GB) were studied. It was revealed that in GB,
55.8% of patients had A type, 45.2% had a type of character. Among men, type A persons prevail, among wom-en - B type. In GB, mild depression is diagnosed in 11.9%, moderate depression in 21.4%, moderate depression
in 35.7% and severe depression in 30.9% of patients. The frequency and severity of depressive symptoms in GB
depends on the complications of the disease. At PIKS (75,0%) in comparison with patients with angina (66,0%)
symptoms of severe and severe depression are more often registered. Deterioration of the systolic function of
the heart and associated heart failure, atrial fibrillation worsen the depressive symptoms

In the study of 168 patients with rheumatoid arthritis, neurotic disorders (ND) were found in 65.6% of patients: 22.6% - weak, 31.7% - moderate and 14.9% - severe degree. The most frequently diagnosed asteno-vegetative disorders are 61.3%. In 24.4% of patients, asthenovegetative symptoms were combined with emo-tional symptoms, 14.3% had hypochondriacal symptoms, 9.5% had hysterical symptoms, and 4.8% had obses-sive disorders. With ND of an easy degree, complex treatment was performed with the use of restorative drugs, physiotherapy and physiotherapy procedures, medium degree - with sedatives (novopassit, sedavit, glycin, adaptol), expressed degree - with antidepressants. At the end of treatment (10-21 days) of all patients with ND in 66 (54.1%) was complete, 44 (36.1%) - a significant reduction in symptoms. In 12 (9.8%) patients, the symp-tomatology of ND did not improve. After the course of complex treatment in 11.5% of patients the result was
assessed as unsatisfactory, 26.2% - satisfactory and 62.3% - positive. In the control group (46 patients without
ND), these results were obtained respectively in 10.8, 37.0 and 52.2% of patients

The problem of perinatal hypoxic lesions of the Central nervous system whose frequency ranges from 73,6% to 90,0% , continues to be one of the most actual in paediatrics. This article examines a method of diag-nosis of intracranial hemorrhage based on the determination in biological fluids neopterin, known as a marker of activity of cell-mediated immunity

In children of different seizure States occur 5-10 times more often than adults. For "teenage" epilepsy, in contrast to the "children's" not typical atonic and tonic seizures. Children and adolescents, patients with epi-lepsy should be the object of a competent psycho-correctional work. A comprehensive study of health and so-cial problems allows us to offer a system of measures aimed at prevention and improvement of organization of neurological care to children and adolescents with epilepsy

The article describes iron deficiency anemia in adolescent girls, characterized by various disorders of the autonomic nervous system: Manifested dysfunction suprasegmental level. Encephalopathies syndrome is characterized by mnestic-intellectual disabilities, as well as preferential interest coordinatory systems, which depend on the severity and duration of the disease

A total of 67 infants aged from birth to 35 days of life. The main group consisted of 50 children with cer-ebral ischemia of I-III degree, control group - 17 healthy newborns.The findings suggest that the studied pa-thology, as a rule, is the result of the influence of the aggregate ante- and perinatal influencing factors. These factors include: age over 30 years old nulliparous abortion, the threat of termination of pregnancy, chronic adnexitis, fast delivery and anemia in pregnant women.This study made it possible to identify the most im-portant risk factors for cerebral ischemia in newborns, distribute them to rank place and calculate the risk and severity of the disease.

The degree of the effect of thyroid hormones (TG) metabolism in general, and asthma. Our results allow to predict the development of distireoza with a tendency to decrease thyroid hormone production in patients with bronchial asthma (BA) even in the absence of clinical symptoms of hypothyroidism

42 children aged from 7 to 16 years old with phlegmons maxillofacial area have been included to inves-tigation. After lancing of the purulent focus we locally used gauze turunda impregnated in 1% solution essen-tial oil of Anise on the apricot oil. Qualitative and quantitative bacteriologic examinations have been carried out on 1, 3, 5 and 7 days after surgical operation. Bacterized of the wound in the basic group of treatment has dramatically reduced especially regarding anaerobe flora by decreased number of bacteria more than 3 times. Local use of essential oil of Anise is shortened duration of hospital treatment in 3±1 days

Objective: to determine the level and dynamics of the main markers of endothelial dysfunctions in pa-tients with congenital mitral valve prolapsed (MVP) with congenital mitral valve prolapsed with undifferentiat-ed connective tissue dysplasia, followed by the application and evaluation of efficacy of magnesium. We exam-ined 86 patients aged 15 to 25 (19.5±1.42) years from the primary etiological features MVP. Survey group in-cluded 41(47,7%) patients with MVP regurgitation of 1 degree and 45(52,3%) patients 2 degree. Patients in each group was administered the drug magnesium (Magnerot firm “Worwag Pharma“) at a daily dose of 3g. per day for 6 months. Patients with congenital MVP were marked signs of endothelial dysfunction (reduction of nitric oxide, increased endothelin-1) and damage it (increasing of concentration of vascular endothelial growth factor VEGF). Therapy with magnerot led to an improvement in endothelial function and prevent progression of endothelial damage

Expansion of the cup pelvis system, ventriculomegaly, hepatomegaly, cardiomegaly with hydropericardi-tis, the emergence of the linear hyperechoic inclusions periventricular regions of the brain of the fetus - the most significant markers predict the birth of a child with IUI.

With acute diseases of the abdominal cavity, 10 patients were hospitalized, 4 of them for acute appendi-citis, 3 for perforated ulcers, 1 for acute cholecystitis, 1 for gastrointestinal bleeding and 1 for infiltrates and
phlegmon retroperitoneal space. Studies were conducted to analyze the immune status of patients taking into
account the phagocytic activity of neutrophils, humoral and cellular immunity. HIV infection is not an excuse
for refusing surgery in patients with acute surgical pathology. Observations showed that the HIV-associated
infection burdens the course of the postoperative period. In patients, there is a prolonged phenomenon of intox-ication, pain, prolonged course of suppuration of the wound, as well as a difficult cleansing of the wound

It is established that the integrated approach to prevention of caries of teeth at children including as hy-giene of an oral cavity, normalization of a microflora, the healthy nutrition and timely implementation of dental procedures allows to prevent in due time various pathology of teeth at children's age

In this article beats the VCC (violation of cerebral circulation) hypotholamic – pituitary-ovarion system in female patients of different age with disorders of brain blood circulation. For this, we take the pituitary gon-adotropic (LG,FSG) and estradiol from blood plasme in two phase: the follicle and lutein of them menstrual cycle and held from radio immunological examination. Hormonal level violations occuring different groups of women with the diagnosis of stroke. This changes may lood to activation such hormones as : honodotropins and estradiol in second phase of menstrual cycle. During violation of blood circulation in the brain of second-ary and adult two men pituitary estradiol hormones are 2-3 times lower than usually were diagnosed. In addi-tion the result of research showed that here is high level of panicin they young sick women

Immunodeficiency arisen because HIV accelerates HBV. In limited to users with mixed infections of HIV and HBV, there is a clear inflammation liver tissue and fibrosis processes clinical features chronically hepatitis have been studied in patients with HIV infection. In diseases like hepatitis B chronically co infection HIV pa-tients with overt clinical signs of hepatitis B is not observed, the disease is on the background of associated diseases and symptoms of drug abuse. HIV exacerbates HBV infection. Infection with HBV and HIV affects in the main reproductive and working-age segment of the population. As a consequence carries problems not only social, but also economic.

In the lungs, of children in early age, with inflammatory pathology, endocrine structures are detected with more regularity and their number is large. As longer the duration of the disease, more apudocytes and neuroepithelial bodies are found in the bronchi and the respiratory part. Inflammatory lung diseases in early postnatal ontogenesis are a predisposing factor for hyperplasia of apudocytes

The object of the study were 90 white rats at the age of 4-6 months. The morphological changes of the pancreas and the walls of blood vessels of the lower limb in experimental diabetes mellitus. Model of experi-mental diabetes reproduced by single intraperitoneal administration of streptozotocin Wistar rats at a dose of 60 mg / kg. Comparison of the mass of bodies of rat control and experimental group showed that during the experiment, the experimental group of rats had plenty in development compared to the control group by 1.7 times. In all the experiments in terms of pancreatic islets was observed moderate lymphocytic infiltration. Mor-phological examination of the vessels in different time postnatal ontogenesis demonstrated that compared with the control group in the form of changes in the delay of progression and formation of individual components vascular wall. Destructive changes in the arterial wall marked us all experimental animals from the early days after the experiment

The effect of defoliant butyphos (I), dropp (II), butylcaptacs (III), hinazopin (IV), tetra-n-butylammonium bromide (VI), etrel (VII), gemetrel (VIII), allyl-4-methylpyridinium bromide (IX), 1-aminocyclopropan-1-carbonate (ACPC) (X) at various concentrations .(1.10-5-2.10-4 M) on respiration, oxidative phosphorylation (OP) and permeability of the inner mitochondrial membrane from rat liver has been studied. It has been estab-lished that some of the compounds uncouple OP by increasing the inner mitochondrial membrane permeability for H+ (II) inhibit the respiration in V3 condition and induce less selective permeability for a number of ions (I,III). The other defoliants either induce respiration generally in metabolic states 3 and 4 (IV, VI, IX) or have no effect on the respiration and OP (V, VII, VIII, X). On the whole a good correlation between the common tox-icity of the studied preparation (LD 50 ) and their mitochondrial effect has been revealed, therefore the latter can be considered as intracellular targets involved in the realization of pesticide action

Broncho-obstructive syndrome is an urgent problem in pediatrics and occupies one of the first places in the structure of respiratory diseases in young children [1,3,5,10,20]. This is due to the wide prevalence of biofeedback in the general structure of bronchopulmonary diseases, severe course and complications. In children of the first years of life, up to 30-50% of acute respiratory infections are complicated by BOS, the main cause of which is acute obstructive bronchitis (AOB) [2,9,11,21]. Most diseases of the bronchopulmonary system occur with biofeedback, among which should be noted congenital and hereditary pathology of the respiratory system, malformations of the bronchi, respiratory distress syndrome, primary immunodeficiency states, aspira-
foreign bodies, perinatal pathology, gastroesophageal reflux, increased intrathoracic lymph nodes, thymus hyperplasia, tumors, etc. [2,3,24]. The uniformity of clinical symptoms of bronchial obstruction in these diseases complicates early diagnosis and treatment tactics, which can lead to a protracted and recurrent course of some of them.

The number of patients with benign neoplasms of the nasal cavity (PN) and paranasal sinuses (SNP) has recently been increasing and amounts to 8-10% of all neoplasms of the head and neck, and, as a rule, they are diagnosed late, taking them for various others, usually inflammatory diseases, due to which the majority of patients (70-90%) come to the clinic with an already widespread tumor process. Vascular tumors of the upper respiratory tract occupy the first place among benign neoplasms in this area in terms of frequency of cases; the mucous membrane of the nasal cavity is most often affected (78%). Hemangiomas are more common in females. This suggests that sex hormones are important in the genesis of vascular tumors. According to the WHO international histological classification, hemangiomas are divided into the following types: capillary, cavernous and venous. The color of the hemangioma depends on its histological structure; the capillary hemangioma is light red in color with clear contours and a smooth surface. Cavernous and venous hemangiomas differ in different shades of blue. Their surface is bumpy, and the contours are not clear

Arrhythmia is a violation of the sequence and frequency of heart contractions. The human heart contracts in a certain mode. This mode forms the conducting system of the heart. It represents knots and bundles of nervous tissue - accumulations of nerve cells and fibers located in areas of the myocardium, which generate bioelectrical impulses in the heart and conduct them [4,10]. There are the following types of arrhythmias: sinus (tachycardia, bradycardia, extrasystole), atrial fibrillation (AF) of the atria or ventricles, paroxysmal tachycardia, heart block [8].

Endometrial hyperplastic processes (HPE) are among the most common gynecological diseases, occurring with a frequency of 30 to 55% [1,4,5,7]. Endometrial hyperplasia (EH) is a well-known problem in gynecology. Despite the large number of studies devoted to the study of the etiology and pathogenesis of the disease, the mechanisms of the formation of the pathological process in endometrium is not completely clear, therefore, approaches to the management of patients are not unambiguous and not standardized. ( 10, 13.14)

Socio-ecological factors lead to a progressive increase in the number of diseases in humans and animals and actualize to an increasing extent the problem of obtaining biologically active substances for the correction of metabolism and immunity [13]. Research scientist Academician V.P. Filatov and his colleagues discovered a new group of natural biologically active substances called "biogenic stimulants". These drugs have found their application in various fields of modern clinical medicine in the form of preparations of plant, animal, and mixed origin [9].

Systemic lupus erythematosus (SLE) is one of the most severe systemic diseases of the connective tissue, more common at the age of 20-40 years, about 90% of cases are women [1;2]. Over the past decades, there has been an increase in the incidence of SLE (50-250 cases per 100 thousand population), which is due to the improvement of diagnostic methods, the identification of latent and chronic forms, and in some cases, overdiagnosis. The diagnostic criteria of the American College of Rheumatology (ACR) (1982, 1997) were developed for epidemiological studies and do not always allow one to exclude or confirm the diagnosis of SLE with absolute probability, especially in the early stages and in atypical variants of the disease [3;4] . When studying the medical records of one of the major medical institutions, J. Calyo et al. [5] found that among patients with a diagnosis of SLE, only two-thirds met the criteria for ACR, while about 10% had signs of lupus that were not sufficient to verify a reliable diagnosis, and 25% had a picture of fibromyalgia in combination with positive antinuclear antibodies (ANA), while even with long-term follow-up, no evolution of the disease into reliable SLE was noted. The question of improving the criteria for diagnosing SLE, “chameleon disease”, or “great disease simulator” has been repeatedly raised [6]. In 2012, a group of experts from Systemic Lupus International Collaborating Clinics (SLICC) presented the results of a long-term analysis of a large number of case histories (about 700 patients) with SLE and proposed modified diagnostic criteria for the diagnosis, expanded by introducing a number of dermatological , neurological signs with more accurate indicators [7;8].

Bleeding from duodenal ulcers is the most formidable complication and occupies one of the first places in the structure of mortality from duodenal ulcer. The anamnestic, clinical features and pH indices in children with duodenal ulcers were studied. 42 children of the senior school age with duodenal ulcers were examined, of them 12 had a complication in the form of ulcerous bleeding. The study makes it possible to consider the sex, age, heredity, erosive nature of gastroduodenitis, multiple ulcers, high bacterial contamination, low pH in the anthroduodenal zone as predictors of complicated course of JBD

2329 women of 50 to 80 years of age, who were in menopause and lived in various regions of the Repub-lic. Prevalence of osteoporosis among surveyed postmenopausal residents comprised 33.4%, osteopenia -34.0%. The number of women with normal BMD significantly declines with the increase of age (86.2% at age of 50-59 years, to 1.3% - at ≥70 years). Nearly third of women (31.8%) regularly consumed dairy products, and slightly more than half (54.7%) lead an active lifestyle. Irregular consumption of dairy products, low phys-ical activity and the duration of menopause were the risk factors in the studied group of women

Objective: to examine the epidemiological characteristic of epilepsy, depending on age and sex in the face of Samarkand. Materials and methods: Object of research was a population of the adult population living in territory of Samarkand for January 1st, 2008 an aggregate number 55232 persons. The results of the analy-sis of the incidence of epilepsy for three years in a given population (2008-2010 years) shows that the method of monitoring population incidence rates higher than with medical history analysis. Conclusions: The preva-lence of epilepsy in the dynamics of the studied population according to age and sex was characterized by a predominance in all age groups of men.

Annotation: Presents the results of the analysis of the age structure, nosologic form, accompanying dis-eases of patients hospitalized in therapy departments Samarkand branch republican research centre of emer-gency medicine. An analysis of hospitalized patients suggests that the main place is occupied by person’s hos-pitalized elderly, and a significant place in this age is given to a chronic pathology of the cardiovascular sys-tem. Severe space also occupied by acute inflammation of the airways, possibly reflecting the immunological "trouble" in the population of older persons

In children with small heart anomalies the most frequently detected mitral valve prolapse, anomalously located left ventricular chord, associated anomalies with the presence of mitral valve prolapse and intra-ventricular formations. Identified adverse factors influencing the occurrence of small heart anomalies, low ex-ercise tolerance, the effect of the small heart anomalies in the development of cardiac arrhythmias in the form of supraventricular and ventricular arrhythmias, supraventricular ectopic rhythm or migration of pacemaker, sinus bradycardia, atrioventricular block 1-2 degree, bundle branch block, QT interval prolongation of more than 440 ms

In order to the study of the state of thyroid remnant in the remote time after the operation at multinodu-lar colloid goiter, it was examined 82 patients at the age of 29 to 64. Revealed that in patients by multinodular colloid goiter in 6 months after the different volume of operations in thyroid remnant according to the ultra-sound revealed 3 types of volume- structural changes (stable- 48,8%, hypertrophic- 28%, hypotrophic- 23,2%)

Analysis results was performed in 116 patients with cholelithiasis complicated by mechanical jaundice who were on the treatment in the city medical association between 2014 on 2016. As a supporters of the two-stage approach to the treatment of mechanical jaundice, the first stage we carried out decompression and sani-tation biliary tract. Preference gave endoscopic retrograde intervention. Endoscopic papillosphincterotomy carried out in 68 patients (58,6%) combined with choledocholithoextraction in 39 patients (57,3%). We consid-er, that at mechanical jaundice the best is two-stage approach with the using of minimally invasive treatments. Operation of choice is endoscopic retrograde intervention with the subsequent cholecystectomy with mini ac-cess. In the impossibility of the decompression is carried out drainage of biliary with the restoration of contin-uous passage of bile in the intestines with laparotomy after stabilization of the state of the patient

All newborns underwent standard laboratory and instrumental examination. Ultrasound examinations (brain, heart, abdominal organs), according to indications, electroencephalography was performed. In the presence of hypoxemia and mixed acidosis of newborns with respiratory distress syndrome, the use of spontaneous breathing with SDPPD improved the overall condition of newborns. This was confirmed by an improvement in the clinical and laboratory and radiographic data of each newborn. Spontaneous breathing with SDPPD is a technically simple and effective method of correction of hypoxemia in the syndrome of respiratory disorders

The article presents the analysis of clinical, laboratory and ultrasound studies of prolonged neonatal jaundice in newborn with prenatal infection proved by biochemical methods, and its clinical conditions in 60 newborn in Samarkand clinics (2014-2016). It was established that newborns with prolonged neonatal jaundice in newborn with prenatal infection are in risk group of severe infection, they require intensive care. It determinates the necessity of the infection specific prevention in newborns prolonged neonatal jaundice in newborn with prenatal infection with the help of policlinics

A total of 50 children with obesity and hypertension were examined comprehensively. It was revealed that in this category of children there is a high growth, acceleration of the rates of sexual development, a de-crease in the quality of life and a greater frequency of pathology from the side of the cardiovascular system in the form of functional disorders and increased blood pressure. Biochemical studies showed that one-third of children with abdominal obesity had a pathology of carbohydrate and lipid metabolism, which was accompa-nied by an increase in the level of uric acid in the blood

Chronic cerebral ischemia (CCI) - a condition manifested by progressive multifocal disorder of brain function caused by cerebral circulatory insufficiency. The article gives a rationale for the use of intravenous ozone therapy in the complex treatment of patients with HIM at different stages of the disease, the study of the dynamics of the changes arising from the use of ozone therapy.

The effectiveness of the drug urapidil in the complex treatment of hypertensive crisis, complicated by acute hypertensive encephalopathy in the clinic of emergency therapy and neurology was studied. The results of the use of the drug urapidil in the complex therapy of hypertensive crisis complicated by acute hypertensive
encephalopathy indicate more effective achievement of the target figures of arterial pressure, rapid and pro-nounced regression of neurological symptoms, rapid activation of consciousness and reduction of the duration of stay of patients in the hospital

The aim was a comparative study of the variability of some taxonomic characters sown E.coli from sick women urinary tract infections. It was found that E.coli strains isolated from different habitats of the body healthy and sick women with varying frequency detected taxonomic characteristics, which are associated with the adhesiveness of the pathogen. The strains exhibit variability mainly by fermentation of mannitol, sucrose, arabinose, glucose, sodium citrate, hemolytic activity.

The effectiveness of using computer tomography in the complex examination of 60 patients with chronic
recurrent hematogenic osteomyelitis aged from 7 to 22 years old have been analyzed in the investigation. Com-
puter tomography as opposed to plan radiography allowed us more precisely determine the real sizes of de-
structive process in the injured bone. In all cases computer tomography has exceeded plan radiography to de-
termination of small sequesters, supporting chronic inflammation and promoting hard recurrent course of the
disease. Used examination method provides the highest accuracy of detection of purulent-necrotic changes in
the affected bones and increases the role of radial methods of diagnostics in developing a set of treatment
measures, including the scope and tactics of surgical intervention in chronic recurrent hematogenous osteomy-
elitis

The Study was performed in 59 children aged 3 to 18 years, located in the Nephrology unit of the Samar-kand regional children's diversified medical center with a diagnosis of chronic glomerulonephritis. N in the period from 2012 to 2016. The composition of the studied children: girls 38 from 3 years to 18 years and boys 21 from 5 years to 18 years. Conducted a comprehensive study of clinical and functional state of the heart on the basis of anamnestic, clinical, laboratory and instrumental parameters in children with chronic glomerulo-nephritis. It is found that increasing the level of uric acid leads to hypertrophy of the ventricles of the heart, vegetative-vascular dystonia, arrhythmia, arterial hypertension, atherosclerosis. cardiovascular disease in
children with chronic glomerulonephritis

73 women after massive obstetric bleeding concerning a preeclampsia of heavy degree 31 (42,4%) wom-en, a premature amotio of a normally located placenta 15 (20,5%), central and low an arrangement of a pla-centa 14 are examined (19,2%), anemia of heavy degree of 13(17,8%). Patients are divided into 2 groups: the 1st group – women of 22(30,1%), transferred organ-preserving operations with the bleeding stop purpose, the 2nd group – women, 51(69,8%) had massive bleeding with a stop by conservative methods, without laparoto-my. Use of traditional treatment-and-reabilitation measures leads to improvement of indicators of quality of life after the complicated labors at 15,4% of women. Application of conservative methods of a stop of bleeding, organ-preserving volume of surgeries allows to increase this indicator to 73,3%.

The analysis of the effectiveness of complex treatment of 66 patients with papillomas of the nose and pa-ranasal sinuses was carried out. In the main group of patients, traditional therapy was supplemented by inges-tion of tyloron (Lavomax) according to the scheme and topical application of Viferon ointment. Immunological studies, as well as data of subjective evaluation, revealed high results in patients of the main group. The con-clusion is made about the possibility of using the preparation of Tyloron (Lavomax) and topically Vifeiron ointment in the complex treatment of nasal and sinus papillomas.

The study included 38 women who underwent cesarean section in a maternity complex №2 city of Samarkand was held. Women were selected for intraoperative IUD. Of the 38 women were 22 urban, 16 rural women. 13 women had higher education, 25 secondary education. In 14 women in history had one pregnancy, in 14 women 2 pregnancies, in 8 women 3 pregnancies, and the remaining 2 women 4 or more pregnancies, ie all of the women were pregnant again. In 4 women had a history of abortion 1. IUD proved to be very safe and effective method of contraception. The level of spontaneous expulsion was lower than the interval introduction. Analysis of surveillance results for patients with IUD allowed to establish a high contraceptive effectiveness of the method, the cases of pregnancy is not registered in any case.

In order to develop evaluation criteria transient evoked otoacoustic emission (TEOAE), including in the age aspect, we conducted a study of the impact of ipsilateral suppression of TEOAE to change its setting. In all cases, after a series of studies there wasa decrease of the total value of the amplitude of TEOAE. The best crite-rion for assessing TEOAE is the construction a tuning curve of the ipsilateral suppression

Objective: comprehensive evaluation of the effectiveness and safety of spinal anesthesia (SA) in the rapid
elimination of discogenic hernia. Material and methods: The basis of the clinical trial data are laid 65 patients with spinal disorders and spinal cord in the lumbar and sacral levels. Depending on the type of anesthesia used (CA or total intravenous anesthesia (TIA) with mechanical ventilation (MV) endotracheal way + О2), the patients were divided into two groups. Results: The research revealed that just before surgery in all patients s-BP, d-BP, m-BP, HR, SpО2 was
within the normal range. These results suggest that the TIA with ventilator endotracheal way + О2 does not
fully ensure the full protection of the body from operating aggression. CA isobaric with 0.5% solution of bupi-
vacaine in a dose of 15 mg 20 provides anesthesia beginning 5-8 min lasts 2-3 hours. Patients were observed
clinically significant disorders of respiratory function and hemodynamics. Conclusion: The described technique allows to carry out surgery safely and effectively

In pregnant women with cervicovaginal infection develops the syndrome of endogenous intoxication (EI),
there is an increase of malondialdehyde (MDA), the average mass of molecules (MSM) 254, and MSM280,
MDA / catalase, with a decrease of catalase and protein stability factor, reducing the performance of the kal-
likrein-kinin system (KKS) - prekallikrein, kallikrein, an increase BAEE, GATA, kininase; they all depend on
the state of the autonomic nervous system (ANS), the largest changes are observed in gipoadaptivе condition.
The study of EI parameters and enzymes ККS can be a predictor of assessing the state and the course of preg-
nancy and the severity marker of inflammation in pregnant women with cervicovaginal infection

Ultrasonic angiography in nephrotuberculosis is a highly informative method in assessing renal blood flow. The use of ultrasonic angiography in the destructive forms of tuberculosis of the kidneys allows us to specify the tactics of management and treatment of patients

89 magnetic resonance tomograms, which were performed by 72 patients with TS, were analyzed. A spe-cific process was localized in the cervical spine in two patients, in the thoracic and thoracolumbar - in 38, in the lumbar and lumbosacral in 32 patients. Isolated lesions of one or two vertebrae were observed in four cas-es, contact destruction in 48, a combination of contact and isolated destruction at 15. Combination of MRI and X-ray methods broadens the notion of morphological changes in the spine, the stage of the tuberculous process, allows one to study the patterns of development And the dynamics of TC, the effectiveness of conservative and operative treatment

The research basis included results of diagnostics and treatment of 42 patients with traumas and diseas-es of bodies of a belly cavity, for diagnostics and which treatment under indications have been used modern endovideosurgical hemostasis methods. During the spent researches it has been established that the basicmeth-
ods of diagnostics of severity level of intrabelly bleedings and a choice of methods of their treatment are ultra-
sonic, КТ and a videolaparoscopy. As a whole, application endovideosurgical for diagnostics and treatment of
intrabelly bleedings allows to avoid technologies unjustified laparotomy, to lower death rates, to reduce quan-
tity of complications, and also to reduce time of stay of patients in a hospital in comparison of medical tech-
niques by means of open operative access

The analysis of results of treatment of 188 victims with the severe burn injury complicated by thermoin-halation damage of airways which were divided into the main and control groups is carried out. In the main group the programmed sanatsionny fibrobronkhoskopiya from the first hours from hospitalization with a fre-quency of 2-3 times per day depending on weight of thermoinhalation defeat during the necessary period of time were applied. In control group sanatsionny bronkhoskopiya were carried out irregularly, generally on request of the attending physician. Other treatment was identical in both groups. Active application the sanatsionnykh of bronkhoskopiya allowed to reduce statistically significantly the frequency of a purulent trakheobronkhit from 38,1% in control group to 14,0% - in the main group and to reduce a lethality from 93,5% in control group to 68,4% - basically.