No. 4 (104) (2018) Problems of biology and medicine

Статьи

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  Haracteristics of alarm-depressive conditions in patients with ulcer disease and their correction Based on the results obtained, patients with peptic ulcer disease should be referred to the risk group for the development of anxiety-depressive disorders, which it is advisable to consult a psychoneurologist during treatment. With comorbidity of peptic ulcer and anxiety-depressive disorders, in addition to eradication thera-py, psychopharmacological therapy is appropriate for patients

  S Caleda

  52-53

  110   20

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  Burning shock: pathogenesis, clinic, principles of treatment Burn shock is the first stage of burn disease and develops when the surface of the body is affected by an area of 10-15% with superficial and 5-10% with deep burns [6,11,14].

  A Avazov, I Mustafakulov, X Karabaev, Sh Saidov, Х Самиев

  227-231

  810   59

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  Clinical characteristics of patients with urogenital candidosis The goal was to study the main symptoms of urogenital candidiasis depending on gender, place of resi-dence of patients. Installed that the main causes of urogenital candidiasis were endocrinopathy, long-term an-tibiotics and cytotoxic drugs, hypovitaminosis. Specific clinical symptoms of urogenital candidiasis are most often detected in women than in men, without reference to age and place of residence

  F Nuraliev

  100-103

  103   24

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  The modern aspects of surgical treatment esophageal cancer The presented article is devoted to the actual problem, that is surgical treatment of esophageal cancer as well as discussion of the modern classification of this pathology, the evaluation of role and perspectives of the newest technologies in esophageal cancer treatment. The analysis of indications, volume of surgical proce-dures and minimally invasive manipulations according to the location and extent of the process in the treatment of esophageal cancer were conducted.

  F Nazyrov, Z Nizamkhojaev, O Gulamov

  94-99

  68   23

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  Assessment of the efficiency of surgical treatment of fresh injuries to the biletary ducts An assessment of the effectiveness of surgical treatment of 175 patients with fresh injuries of the main bile ducts obtained during various cholecystectomy methods revealed intraoperatively (51) and in the early postoperative period (124) is presented. The proposed algorithms for selecting the method of surgical treat-ment of patients with fresh injuries of the main bile ducts allowed to reduce the overall frequency of postopera-tive complications in the early and late periods from 56.3% to 23.6% and mortality from 10.7% to 4.2%.

  F Nazyrov, Z Kurbaniyazov, P Askarov

  86-93

  107   19

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  Medical protection of psychoemotional stress in elderly patients with accompanying hypertensive disease in optalmosurgery Among them were 38 women (46.3%) and 44 men (53.7%). The age of patients was 60 to 75 years, the duration of arterial hypertension (AH) was 10 to 23 years. Preoperative preparation of patients with concomi-tant GB, as well as subsequent hemodynamic monitoring is described. The results of the study suggest that ad-equate antihypertensive therapy in combination with sedation and neuroleptanalgesia in the wards of waiting allows achieving stabilization of the clinical state of patients, clearly correlating with improvement of hemody-namic parameters

  N Mukhamediev, M Matlubov, E Khamdamov

  83-85

  171   25

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  Elaborating of endoscopic treatment algorithm of patients with staghorn and multiple kidney stones Complex examination and treatment of 158 patients with staghorn and multiple kidney stones was car-ried out. The use of endoscopic treatment algorithm in patients with staghorn and multiple nephrolithiasis al-lowed to increase the stone free rate up to 90.0%. Inclusion of developed algorithm of endoscopic treatment of patients with staghorn and multiple kidney stones in the complex of therapeutic measures allows to increase the effectiveness of treatment of patients with nephrolithiasis

  D Mirkhamidov, F Nasirov, A Shomarufov, Sh Abbosov, O Abdukarimov, B Turaev

  79-82

  106   24

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  Tactics of patients with cardiogenic shock The article highlights the actual problem of diagnostics and treatment of cardiogenic shock. A number of measures of a therapeutic and diagnostic nature are given

  N Makhmatmuradova, M Safarova

  76-78

  134   31

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  Condition of metallotroteinazy-1u inhibitor of patients with epitelialny skin tumors in the course of expeditious treatment Work is based on the analysis of a condition of inhibitor of metalproteinase-1 at 185 patients with various formations of skin. From them bazalnokletochny cancer of skin has been revealed at 39 patients, planocellular cancer of skin – at 39 people, good-quality education is skin (fibroma) – at 48 patients (group of comparison 1). In addition, researches at the 34th rather healthy the donor volunteer have been conducted (group of comparison 2). Most of patients were male and 50 years are more senior. The greatest number of educations – 25% has been noted on the lower extremities. Concerning educations on a face have asked for medical care of 15% of patients. It should be noted that at the vast majority of patients of this group malignancies have been revealed. As a result of the conducted research it has been established that in pathogenesis of development of any tumoral process of skin increase in TIMP-1 lies. Expeditious treatment at fibroma of skin leads to decrease in TIMP-1, since third postoperative day. Performance of surgical treatment at basal and cellular cancer of skin leads to partial decrease in TIMP-1 since fifth postoperative days. At planocellular cancer of skin occurs, increase in TIMP-1 since first postoperative days, decrease by tenth postoperative days. At the same time performance of expeditious treatment doesn't lead to decrease in TIMP-1 in the remote postoperative period.

  V Maslyakov, L Kim

  72-75

  100   16

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  Optimization of ovulation induction in infertile women with edocrine sterility Today, the diagnosis of polycystic ovary syndrome is based on the provisions of the Rotterdam Conven-tion (2003) and includes, above all, the diagnosis of hyperandrogenism and oligo / anovulation, which do not allow for the implementation of reproductive function. Other manifestations of PCOS associated with insulin resistance and dyslipidemia continue to be widely discussed in the literature. And since the frequency of infer-tility in women with hyperandrogenism and anovulation reaches 90%, the issues of treatment of such patients are highly relevant and require a comprehensive solution. This article focuses on the treatment of anovulation through the introduction of ovulation inducers. Research in the field of reproductive gynecology was the basis for the synthesis and clinical use of drugs that stimulate ovulation, and thus, make it possible to realize the gen-ital function

  M Kurbaniyazova, P Saparbayeva

  69-71

  150   44

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  Factor analysis of the frequency of damage to bilitary channels in surgery of gulk-stone disease The analysis of the frequency of fresh injuries and the formation of cicatricial strictures of the main bile ducts in gallstone surgery is given. The probability of damage to the bile duct in surgery for gallstone disease was 0.38%, the incidence of post-traumatic cicatricial stricture - 0.37%. A significant difference in the fre-quency of these complications was determined depending on the type of operations and inflammation in the gallbladder, as well as on the urgency of the operation

  Z Kurbaniyazov, П Askarov

  63-68

  108   20

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  Protocol of prenatal ultrasound diagnostics of congenital defects of the heart of the feta Early fetal echocardiography, performed between 12 and 16 weeks of gestational age, is technically pos-sible using the heart ultrasound protocol and can identify a wide range of significant heart abnormalities. In addition, it allows to evaluate the progression of the disease and, given the beginning of the widespread use of intrauterine interventions, can provide an earlier and effective fetoscopy

  Sh Kamalidinova, A Fazylov, V Dyakov

  59-62

  219   30

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  Efficiency of ultrasound screening for development faults and chromosomic anomalies In order to avoid undeveloped pregnancy, and intrauterine fetal death, as well as early detection of fetal malformations, there is a need for screening in the first trimester of pregnancy. Inclusion of the first trimester in the screening program in a timely manner will create risk groups for the birth of children with malfor-mations of the fetus, timely resolve the issue of further introduction of pregnancy, thereby reducing obstetric complications, and also reduce maternal and infant mortality

  Sh Kamalidinova, A Fazylov, G Azimova

  54-58

  133   25

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  Сlinical-neurological, neurophysiological features of symptomatic epilepsy The article considers the state of epileptic seizures and diagnostic indices of patients with epilepsy of ob-servation in 25 patients. The frequency of development of the disease was determined by various epileptic sei-zures. It was also based on the results of an EEG study of patients with a very important diagnosis of epilepsy. Most often, clinical manifestations of attacks were absans and focal motor attacks. The article describes the main pathological changes in the bioelectrical activity of the brain

  R Azizova, N Abdullayeva, X Gafurova

  8-9

  107   23

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  Early stage of kidney damage in patients with hypertensive disease The defeat of the kidney as the target organ of hypertensive disease in 40% of patients begins to form early - within 5 years from the debut of the disease. The early stage of hypertensive nephropathy is a dynamic process that has clinical and functional markers at each stage, so microalbuminuria, increased intrarenal vas-cular resistance, and changes in the total filtration function of the kidneys are the earliest

  L Kadomtseva, S Pulatova, E Tukhvatulina

  49-51

  119   21

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  Complex research in the diagnostics of chronic viral hepatitis in children The object of the study were 120 children from 3 to 18 years old, patients with chronic viral hepatitis. General clinical, biochemical, specific laboratory, instrumental, radiation: complex echographic studies, MSCT, MRI, SI of the liver, spleen, biliary tract were used, histological criteria of liver damage, as well as sta-tistical research methods were studied. The use of a set of methods of instrumental methods, along with clinical laboratory and, according to indications, histological studies in chronic viral hepatitis in children, makes it possible to formulate a definitive and reliable diagnosis in the early stages of the disease and carry out ade-quate therapy, prevent complications and transition to a more severe degree of activity or cirrhosis the liver

  F Inoyatova, A Sydikov, G Yusupalieva

  42-48

  90   21

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  Assessment of the functional condition of the fetoplacental complex in women with arterial hypotension using echography and dopplerography While the problem of arterial hypertension in recent years has become one of the most important in med-icine, and in particular in obstetrics, the issues of pathogenesis, clinical manifestations, complications of preg-nancy and childbirth, possible adverse effects on the fetus, as well as the treatment of arterial hypotension, at-tract significantly less attention of clinicians.

  G Indiaminova, G Zhuraeva, K Azimova

  40-41

  178   14

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  Amputation of limbs in heavy-burned The article analyzes the results of treatment of 34 patients with deep thermal lesions of the upper and lower extremities, aged 15 to 65 years. Among the observed patients with deep burns limb amputations were performed in 28 patients on 32 extremities. The indications, the technique of operations, the introduction of the postoperative period, which allows to significantly improve the results of treatment, maximally preserve the function of the affected limbs, will increase the healing possibilities of combobustology for saving the life of doomed patients with uncompensated loss of skin

  Sh Dzhumageldiev, I Mustafakulov, X Karabaev, K Tagaev, M Muhammadiev

  37-39

  171   26

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  Gastroduodenal bleeding in severely burned Gastroduodenal bleeding complicates the course of the burn disease and in some cases may increase the likelihood of death in patients with severe thermal trauma. The analysis of 105 victims with severe thermal trauma (the area of deep burn 20-40%), who were on treatment from 2010 to 2017, in whom the course of the burn disease was complicated by the development of gastroduodenal bleeding. Studies have shown that the pathogenetically substantiated method of choice for the development of massive bleeding in burned patients is endoscopic arrest on the background of complex haemostatic, replacement and angioprotective therapy

  F Daminov, X Karabaev, K Tagaev, I Mustafakulov, E Khakimov

  33-36

  100   12

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  Motor and non-motor damage in the early and late stages of parkinson’s disease In patients with Parkinson’s disease, anxiety disorders investigated at early and late stages. For this, we used the following scales: To measure the severity of the movement the XEN-YARA scale, to check the final stage of motion defection “UPDRS” (Unified Parkinson`s Disease Rating Scale).As a result, in patients with Parkinson’s disease, anemia and movement disorders develop more often in the late stage of illness than in the earthy stage of the disease

  S Gaffarova, S Sattarova, M Khamidullayeva, S Khakimova, I Mamurova

  29-32

  189   23

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  The medicinal plants in the management of urolithiasis The medicinal therapy for urolithiasis should be long-term. The significant side effects of synthetic drugs often requires discontinuation of treatment. Therefore, of the preference is given to herbal medicines. The diu-retic and saluretic abilities of infusions from 15 medicinal plants of the flora of Uzbekistan were studied during treatment of 449 pts with calcium urolithiasis. Infusions has different diuretic power, as well as effects on urine pH and saluresis. The revealed properties of the preparations made it possible to develop criteria for their ad-ministration taking into account the state of diuresis, urine pH, balance of promoters and calcium stone for-mation inhibitors. The selective treatment contributes provide the high therapeutic efficacy and economic bene-fits.

  A Gaibullaev, S Kariev

  25-28

  78   23

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  Clinical diagnostic features of cns infectious defects in hiv-infected patients Among the observed patients, the predominant route of HIV infection was injection. The Epstein – Barr virus, Toxoplasma and Mycobacterium tuberculosis were the most frequent pathogens affecting the CNS in HIV-positive patients. The disease developed mainly in young people, regardless of gender. Infectious lesions of the CNS in HIV-positive patients develop gradually and manifest themselves clinically against the back-ground of deep immunodeficiency

  A Baizhanov, S Utegenova

  23-24

  81   18

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  The study of erythrocytes forms at patients with the arterial hypertension Using of express method of thick drop the proportion of the normal and pathological forms of erythro-cytes were studied. It was shown that in arterial hypertension the part of pathological forms of erythrocytes increases and the part of normal erythrocytes decreases. It is more obviously in second and third degrees of the arterial hypertension

  I Baibekov, D Rakhmanov

  20-22

  140   17

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  Assessment of the functional condition of kidneys in patients with excessive body weight and obesity The aim was to study the functional state of the kidneys with overweight and obesity. It was established that the average parameters of the GFR of the examined changed along with the growth of the BMI for all types of GFR. If, when calculating according to the MDRD and CKD-EPI formulas, significant differences between the groups were obtained, then, when calculating using the Cockcroft Gault formula, no significant differences were observed. Calculations of GFR using MDRD and CKD-EPI formulas revealed 1.5 times more patients requiring special nephrological examination, treatment correction, and dynamic observation. The calculation of GFR using the MDRD and CKD-EPI formulas is preferable to the calculation using the Cockcroft-Gault metod.

  N Ahmedova

  16-19

  113   33

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  Evaluation of initial vegetative tone in children perennial allergic rhinitis on clinical signs tables Were studied the state of the initial autonomic tone in children perennial allergic rhinitis. Among 42 patients (68,9 per cent) were persistent, and 19 (31,1 per cent) – intermittent form CT. According to the analysis of clinical signs IWT in 28 (54.9 per cent) of children identified CT status, the prevalence of parasympathicotonia (vagotonia), 28(54,9per cent) - eatonii (balanced state of the ANS alone) – 9 (17,6%) of sympathicotonia. In General, CT is not dependent on clinical course, characterized by increased tension of the parasympathetic mechanisms of the ANS. the results indicate about the relationship between IWT and clinical course CT. You can assume the existence of a similar connection with the treatment CT

  A Arifov, A Daliev, G Tuychiev, X Kosimov, L Nizomov

  13-15

  74   28

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